[HTML][HTML] The development of maillard reaction, and advanced glycation end product (AGE)-receptor for AGE (RAGE) signaling inhibitors as novel therapeutic …
CY Shen, CH Lu, CH Wu, KJ Li, YM Kuo, SC Hsieh… - Molecules, 2020 - mdpi.com
Advanced glycation end products (AGEs) are generated by nonenzymatic modifications of
macromolecules (proteins, lipids, and nucleic acids) by saccharides (glucose, fructose, and …
macromolecules (proteins, lipids, and nucleic acids) by saccharides (glucose, fructose, and …
Old wine in new bottles: Kaempferol is a promising agent for treating the trilogy of liver diseases
X Xiao, Q Hu, X Deng, K Shi, W Zhang, Y Jiang… - Pharmacological …, 2022 - Elsevier
As a source of various compounds, natural products have long been important and valuable
for drug development. Kaempferol (KP) is the most common flavonol with bioactive activity …
for drug development. Kaempferol (KP) is the most common flavonol with bioactive activity …
[HTML][HTML] Resveratrol reestablishes mitochondrial quality control in myocardial ischemia/reperfusion injury through Sirt1/Sirt3-Mfn2-Parkin-PGC-1α pathway
M Zheng, Y Bai, X Sun, R Fu, L Liu, M Liu, Z Li… - Molecules, 2022 - mdpi.com
Resveratrol is a natural polyphenol found in various plants. It has been widely studied on
cardiovascular disorders. It is known that resveratrol can activate Sirtuin proteins and …
cardiovascular disorders. It is known that resveratrol can activate Sirtuin proteins and …
[HTML][HTML] Insights into fourth generation selective inhibitors of (C797S) EGFR mutation combating non-small cell lung cancer resistance: a critical review
Lung cancer is the second most common cause of morbidity and mortality among cancer
types worldwide, with non-small cell lung cancer (NSCLC) representing the majority of most …
types worldwide, with non-small cell lung cancer (NSCLC) representing the majority of most …
[HTML][HTML] Resveratrol improves Bnip3-related mitophagy and attenuates high-fat-induced endothelial dysfunction
C Li, Y Tan, J Wu, Q Ma, S Bai, Z Xia, X Wan… - Frontiers in Cell and …, 2020 - frontiersin.org
Statin treatment reduces cardiovascular risk. However, individuals with well-controlled low-
density lipoprotein (LDL) levels may remain at increased risk owing to persistent high …
density lipoprotein (LDL) levels may remain at increased risk owing to persistent high …
An overview of the pharmacological activities of scopoletin against different chronic diseases
Chronic diseases are considered a major public health concern worldwide, and most of
these diseases like cancer, cardiovascular, metabolic, and neurological disorders occur due …
these diseases like cancer, cardiovascular, metabolic, and neurological disorders occur due …
Biological effects and mechanisms of matrine and other constituents of Sophora flavescens in colorectal cancer
Abstract The plant Sophora flavescens Ait. has been used in the clinical management of
colorectal cancer (CRC). Its constituent compounds, notably the alkaloids matrine …
colorectal cancer (CRC). Its constituent compounds, notably the alkaloids matrine …
Recent advances of novel fourth generation EGFR inhibitors in overcoming C797S mutation of lung cancer therapy
L Xu, B Xu, J Wang, Y Gao, X He, T Xie… - European Journal of …, 2023 - Elsevier
Lung cancer is the second place among the global cancer population in term of the
morbidity and mortality, while non-small cell lung cancer (NSCLC) accounts for the largest …
morbidity and mortality, while non-small cell lung cancer (NSCLC) accounts for the largest …
[HTML][HTML] Natural products modulate cell apoptosis: a promising way for treating endometrial cancer
X Zhou, Y Zeng, J Huang - Frontiers in Pharmacology, 2023 - frontiersin.org
Endometrial cancer (EC) is a prevalent epithelial malignancy in the uterine corpus's
endometrium and myometrium. Regulating apoptosis of endometrial cancer cells has been …
endometrium and myometrium. Regulating apoptosis of endometrial cancer cells has been …
[HTML][HTML] Pharmacokinetics and biological activity of cucurbitacins
EE Delgado-Tiburcio, J Cadena-Iñiguez… - Pharmaceuticals, 2022 - mdpi.com
Cucurbitacins are a class of secondary metabolites initially isolated from the Cucurbitaceae
family. They are important for their analgesic, anti-inflammatory, antimicrobial, antiviral, and …
family. They are important for their analgesic, anti-inflammatory, antimicrobial, antiviral, and …