The roles and applications of neural stem cells in spinal cord injury repair
W Guo, X Zhang, J Zhai, J Xue - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Spinal cord injury (SCI), which has no current cure, places a severe burden on patients.
Stem cell-based therapies are considered promising in attempts to repair injured spinal …
Stem cell-based therapies are considered promising in attempts to repair injured spinal …
The role of hypoxia in stem cell regulation of the central nervous system: from embryonic development to adult proliferation
G Li, J Liu, Y Guan, X Ji - CNS Neuroscience & Therapeutics, 2021 - Wiley Online Library
Hypoxia is involved in the regulation of various cell functions in the body, including the
regulation of stem cells. The hypoxic microenvironment is indispensable from embryonic …
regulation of stem cells. The hypoxic microenvironment is indispensable from embryonic …
Microneedle-mediated biomimetic cyclodextrin metal organic frameworks for active targeting and treatment of hypertrophic scars
T Wu, X Hou, J Li, H Ruan, L Pei, T Guo, Z Wang, T Ci… - Acs Nano, 2021 - ACS Publications
Due to the lack of a delivery system that actively targets hypertrophic scar fibroblasts (HSFs),
it is difficult to concentrate the effects of drugs on hypertrophic scars (HSs). We recently …
it is difficult to concentrate the effects of drugs on hypertrophic scars (HSs). We recently …
Akkermansia muciniphila and Lactobacillus plantarum ameliorate systemic lupus erythematosus by possibly regulating immune response and remodeling gut …
M Guo, M Lu, K Chen, R Xu, Y Xia, X Liu, Z Liu, Q Liu - Msphere, 2023 - Am Soc Microbiol
Systemic lupus erythematosus (SLE), characterized by persistent inflammation, is a complex
autoimmune disorder that affects all organs, challenging clinical treatment. Dysbiosis of gut …
autoimmune disorder that affects all organs, challenging clinical treatment. Dysbiosis of gut …
Piezo1 (piezo-type mechanosensitive ion channel component 1)-mediated mechanosensation in macrophages impairs perfusion recovery after hindlimb ischemia in …
Background: Angiogenesis is a promising strategy for those with peripheral artery disease.
Macrophage-centered inflammation is intended to govern the deficiency of the angiogenic …
Macrophage-centered inflammation is intended to govern the deficiency of the angiogenic …
[HTML][HTML] Alginate self-adhesive hydrogel combined with dental pulp stem cells and FGF21 repairs hemisection spinal cord injury via apoptosis and autophagy …
S Zhu, Y Ying, Q Wu, Z Ni, Z Huang, P Cai, Y Tu… - Chemical Engineering …, 2021 - Elsevier
Spinal cord injury (SCI) often leads to persistent functional deficits due to loss of neurons
and glia after injury. Hemisection spinal cord injury (HSCI) is a special type of SCI. The most …
and glia after injury. Hemisection spinal cord injury (HSCI) is a special type of SCI. The most …
Basic fibroblast growth factor‐loaded methacrylate gelatin hydrogel microspheres for spinal nerve regeneration
X Chen, L Ren, H Zhang, Y Hu, M Liao, Y Shen… - Smart …, 2023 - Wiley Online Library
Spinal cord injury is a severe central nervous system injury, and developing appropriate
drug delivery platforms for spinal nerve regeneration is highly anticipated. Here, we propose …
drug delivery platforms for spinal nerve regeneration is highly anticipated. Here, we propose …
Molecular approaches for spinal cord injury treatment
FM de Almeida, SA Marques… - Neural Regeneration …, 2023 - journals.lww.com
Injuries to the spinal cord result in permanent disabilities that limit daily life activities. The
main reasons for these poor outcomes are the limited regenerative capacity of central …
main reasons for these poor outcomes are the limited regenerative capacity of central …
Metformin protects against spinal cord injury and cell pyroptosis via AMPK/NLRP3 inflammasome pathway
Y Yuan, X Fan, Z Guo, Z Zhou… - Analytical cellular …, 2022 - Wiley Online Library
Spinal cord injury (SCI) is an extreme neurological impairment with few effective drug
treatments. Pyroptosis is a recently found and proven type of programmed cell death that is …
treatments. Pyroptosis is a recently found and proven type of programmed cell death that is …
Spinal cord injury management through the combination of stem cells and implantable 3D bioprinted platforms
Spinal cord injury (SCI) has a major impact on affected patients due to its pathological
consequences and absence of capacity for self-repair. Currently available therapies are …
consequences and absence of capacity for self-repair. Currently available therapies are …