Sepsis-Associated Acute Kidney Injury: Where Are We Now?
D Kounatidis, NG Vallianou, S Psallida… - Medicina, 2024 - mdpi.com
Worldwide, sepsis is a well-recognized cause of death. Acute kidney injury (AKI) may be
related to sepsis in up to 70% of AKI cases. Sepsis-associated AKI (SA-AKI) is defined as the …
related to sepsis in up to 70% of AKI cases. Sepsis-associated AKI (SA-AKI) is defined as the …
Therapeutic and immunomodulatory potentials of mesenchymal stromal/stem cells and immune checkpoints related molecules
A Hazrati, K Malekpour, H Khorramdelazad… - Biomarker …, 2024 - Springer
Mesenchymal stromal/stem cells (MSCs) are used in many studies due to their therapeutic
potential, including their differentiative ability and immunomodulatory properties. These cells …
potential, including their differentiative ability and immunomodulatory properties. These cells …
Bone marrow: The central immune system
V Schirrmacher - Immuno, 2023 - mdpi.com
Bone marrow is known as the site of hematopoiesis. What is not being described in
textbooks of immunology is the fact that bone marrow is not only a generative, but also an …
textbooks of immunology is the fact that bone marrow is not only a generative, but also an …
Machine learning reveals the rules governing the efficacy of mesenchymal stromal cells in septic preclinical models
D Gakhar, H Joshi, D Makkar, N Taneja, A Arora… - Stem Cell Research & …, 2024 - Springer
Abstract Background Mesenchymal Stromal Cells (MSCs) are the preferred candidates for
therapeutics as they possess multi-directional differentiation potential, exhibit potent …
therapeutics as they possess multi-directional differentiation potential, exhibit potent …
The role of TIM-3 in sepsis: a promising target for immunotherapy?
C Wang, J Liu, Q Wu, Z Wang, B Hu, L Bo - Frontiers in Immunology, 2024 - frontiersin.org
Sepsis remains a significant cause of mortality and morbidity worldwide, with limited
effective treatment options. The T-cell immunoglobulin and mucin domain-containing …
effective treatment options. The T-cell immunoglobulin and mucin domain-containing …
Th17/Treg balance: the bloom and wane in the pathophysiology of sepsis
X Liu, L Chen, W Peng, H Deng, H Ni, H Tong… - Frontiers in …, 2024 - frontiersin.org
Sepsis is a multi-organ dysfunction characterized by an unregulated host response to
infection. It is associated with high morbidity, rapid disease progression, and high mortality …
infection. It is associated with high morbidity, rapid disease progression, and high mortality …
IL-1β-Stimulated Bone Mesenchymal Stem cell-Derived Exosomes Mitigate sepsis through Modulation of HMGB1/AKT pathway and M2 Macrophage Polarization
Y Li, Z Sun, Y Li, J Sun, B Chen - Current Molecular Medicine, 2024 - ingentaconnect.com
Background: Sepsis is a life-threatening disease caused by infection, and developing novel
strategies against sepsis is still required. Exosomes derived from mesenchymal stem cells …
strategies against sepsis is still required. Exosomes derived from mesenchymal stem cells …
Th17 cells: A new target in kidney disease research
T Zhang, H Huo, Y Zhang, J Tao, J Yang… - International Reviews …, 2024 - Taylor & Francis
Abstract Type 17 T helper (Th17) cells, which are a subtype of CD4+ T helper cells, secrete
pro-inflammatory cytokines such as IL-17A, IL-17F, IL-21, IL-22, and GM-CSF, which play …
pro-inflammatory cytokines such as IL-17A, IL-17F, IL-21, IL-22, and GM-CSF, which play …