Lipoprotein (a) in atherosclerotic diseases: from pathophysiology to diagnosis and treatment

S Lampsas, M Xenou, E Oikonomou, P Pantelidis… - Molecules, 2023 - mdpi.com
Lipoprotein (a)(Lp (a)) is a low-density lipoprotein (LDL) cholesterol-like particle bound to
apolipoprotein (a). Increased Lp (a) levels are an independent, heritable causal risk factor …

[HTML][HTML] Lipoprotein (a): An underrecognized genetic risk factor for malignant coronary artery disease in young Indians

EA Enas, B Varkey, TS Dharmarajan, G Pare… - Indian heart journal, 2019 - Elsevier
Malignant coronary artery disease (CAD) refers to a severe and extensive atherosclerotic
process involving multiple coronary arteries in young individuals (aged< 45 years in men …

Apolipoprotein (a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism

A Helgadottir, S Gretarsdottir, G Thorleifsson… - Journal of the American …, 2012 - jacc.org
Objectives: The purpose of this study is investigate the effects of variants in the
apolipoprotein (a) gene (LPA) on vascular diseases with different atherosclerotic and …

Role of lipoprotein (a) and apolipoprotein (a) phenotype in atherogenesis: prospective results from the Bruneck study

F Kronenberg, MF Kronenberg, S Kiechl… - Circulation, 1999 - Am Heart Assoc
Background—Experimental studies have suggested both atherogenic and thrombogenic
properties of lipoprotein (a)[Lp (a)], depending on Lp (a) plasma concentrations and varying …

Elevated lipoprotein (a)—a genetic risk factor for premature vascular disease in people with and without standard risk factors: a review

EA Enas, V Chacko, A Senthilkumar, N Puthumana… - Disease-a-Month, 2006 - Elsevier
Lp (a) was identified as a novel antigen by Kare Berg in 1963. 1 Mounting evidence from
prospective epidemiologic and clinical studies over the past four decades show that …

Lipoprotein (a) and the atherothrombotic process: mechanistic insights and clinical implications

AM Scanu - Current atherosclerosis reports, 2003 - Springer
Although many epidemiologic studies have pointed at an association between plasma
levels of lipoprotein (a)(Lp (a)) and cardiovascular risk, the data obtained have been …

Analysis of the apo (a) size polymorphism in Asian Indian populations: association with Lp (a) concentration and coronary heart disease

FS Geethanjali, K Luthra, A Lingenhel… - Atherosclerosis, 2003 - Elsevier
Most studies aiming to detect associations of genetic variation with common complex
diseases, eg coronary heart disease (CHD) have been performed in populations with a …

Lipoprotein (a): Better assessor of coronary heart disease risk in South Indian population

D Rajasekhar, KSS Saibaba, P Srinivasa Rao… - Indian Journal of Clinical …, 2004 - Springer
In an attempt to search for risk factors which can explain the increasing prevalence of
coronary heart disease (CHD) in Indian population, we conducted a case-control study to …

− 374T/A polymorphism of the RAGE gene promoter in relation to severity of coronary atherosclerosis

C Falcone, I Campo, E Emanuele, MP Buzzi… - Clinica Chimica …, 2005 - Elsevier
BACKGROUND: We have recently reported that homozygosity for the minor A-allele of
RAGE (receptor for advanced glycation end products)− 374T/A polymorphism may exert a …

Lipoprotein (a), apolipoprotein (a) polymorphism and coronary atherosclerosis severity in type 2 diabetic patients

C Gazzaruso, R Bruno, A Pujia, E De Amici… - International journal of …, 2006 - Elsevier
BACKGROUND: Few and conflicting data are available in the literature on the association
between Lp (a) levels and the severity of coronary artery disease (CAD) in diabetic patients …