Purpose Radiation-induced fibrosis (RIF) is a long-term side effect of external beam
radiation therapy for the treatment of cancer. It results in a multitude of symptoms that …

The development of protective agents against harmful radiations has been a subject of
investigation for decades. However, effective (ideal) radioprotectors and radiomitigators …

Radiation is an important component of cancer treatment with more than half of all patients
receive radiotherapy during their cancer experience. While the impact of radiation on tumour …

Lung malignancy is the foremost cause of cancer-related deaths globally and is frequently
related to long-term tobacco smoking. Recent studies reveal that the expression of matrix …

Radiation-induced lung fibrosis (RILF) is a severe side effect of radiotherapy in lung cancer
patients that presents as a progressive pulmonary injury combined with chronic …

Radiation therapy is one of the most common treatment strategies for thorax malignancies.
One of the considerable limitations of this therapy is its toxicity to normal tissue. The lung is …

In humans, a number of genetic factors have been linked to the development of fibrosis in a
variety of different organs. Seeking a wider understanding of this observation in man is …

Radiation-induced pneumonitis and fibrosis are dose-limiting side effects of thoracic
irradiation. Thoracic irradiation triggers acute and chronic environmental lung changes that …

Purpose Lung inflammation leading to pulmonary toxicity after radiotherapy (RT) can occur
in patients with non-small cell lung cancer (NSCLC). We investigated the kinetics of RT …

Despite their clinical benefits in cancer treatment, the deleterious effects on heart following
chemo/radiotherapy are of increasing importance. Zingerone, a natural polyphenol …