[HTML][HTML] Ticagrelor and aspirin or aspirin alone in acute ischemic stroke or TIA

SC Johnston, P Amarenco, H Denison… - … England Journal of …, 2020 - Mass Medical Soc
Background Trials have evaluated the use of clopidogrel and aspirin to prevent stroke after
an ischemic stroke or transient ischemic attack (TIA). In a previous trial, ticagrelor was not …

Ticagrelor added to aspirin in acute nonsevere ischemic stroke or transient ischemic attack of atherosclerotic origin

P Amarenco, H Denison, SR Evans, A Himmelmann… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: Among patients with a transient ischemic attack or minor ischemic
strokes, those with ipsilateral atherosclerotic stenosis of cervicocranial vasculature have the …

Ticagrelor versus clopidogrel in the dual antiplatelet regimen for intracranial stenting or flow-diverter treatment for unruptured cerebral aneurysms: a single-center …

KY Park, T Ozaki, A Kostynskyy… - American Journal …, 2021 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Ticagrelor is a novel P2Y12 antagonist, and little is known
about its efficacy and safety in the endovascular treatment of aneurysms. This study …

[HTML][HTML] Recent advances in the management of transient ischemic attacks

J Ortiz-Garcia, CR Gomez, MJ Schneck, J Biller - Faculty Reviews, 2022 - ncbi.nlm.nih.gov
Transient ischemic attack (TIA) constitutes an important clinical condition, indicating the
presence of considerable risk for a subsequent ischemic stroke. Its prompt diagnosis and …

Risk for major hemorrhages in patients receiving clopidogrel and aspirin compared with aspirin alone after transient ischemic attack or minor ischemic stroke: a …

H Tillman, SC Johnston, M Farrant, W Barsan… - JAMA …, 2019 - jamanetwork.com
Importance Results show the short-term risk of hemorrhage in treating patients with acute
transient ischemic attack (TIA) or minor acute ischemic stroke (AIS) with clopidogrel plus …

Dual antiplatelet therapy combining aspirin and ticagrelor for intracranial stenting procedures: a retrospective single center study of 154 consecutive patients with …

AP Narata, A Amelot, R Bibi, D Herbreteau… - …, 2019 - journals.lww.com
BACKGROUND Dual antiplatelet therapy (DAPT) associating aspirin+ clopidogrel is
commonly utilized in neurovascular interventions despite unpredictable clopidogrel efficacy …

Time course for benefit and risk with ticagrelor and aspirin in individuals with acute ischemic stroke or transient ischemic attack who carry CYP2C19 loss-of-function …

Y Pan, X Meng, A Jin, SC Johnston, H Li… - JAMA …, 2022 - jamanetwork.com
Importance Dual antiplatelet therapy (DAPT) with ticagrelor and aspirin has been found to
be effective for secondary prevention after minor ischemic stroke or transient ischemic attack …

[HTML][HTML] Recent advances in the management of transient ischemic attacks

CR Gomez, MJ Schneck, J Biller - F1000Research, 2017 - ncbi.nlm.nih.gov
Significant advances in our understanding of transient ischemic attack (TIA) have taken
place since it was first recognized as a major risk factor for stroke during the late 1950's …

Ticagrelor added to aspirin in acute ischemic stroke or transient ischemic attack in prevention of disabling stroke: a randomized clinical trial

P Amarenco, H Denison, SR Evans… - JAMA …, 2021 - jamanetwork.com
Importance Reduction of subsequent disabling stroke is the main goal of preventive
treatment in the acute setting after transient ischemic attack (TIA) or minor ischemic stroke …

The Acute S t roke or Transient Isc h emic Attack Treated with Tic a gre l or and Aspirin for Pr e vention of S troke and Death (THALES) trial: Rationale and design

SC Johnston, P Amarenco, H Denison, SR Evans… - 2019 - journals.sagepub.com
Rationale In patients with acute cerebral ischemia, the rate of stroke, myocardial infarction,
or death during 90 days was reported to be non-significantly lower with ticagrelor compared …