Oxidative stress in intervertebral disc degeneration: molecular mechanisms, pathogenesis and treatment

Y Wang, H Cheng, T Wang, K Zhang, Y Zhang… - Cell …, 2023 - Wiley Online Library
Low back pain (LBP) is a leading cause of labour loss and disability worldwide, and it also
imposes a severe economic burden on patients and society. Among symptomatic LBP …

ATG5: A central autophagy regulator implicated in various human diseases

H Changotra, S Kaur, SS Yadav… - Cell biochemistry …, 2022 - Wiley Online Library
Autophagy, an intracellular conserved degradative process, plays a central role in the
renewal/recycling of a cell to maintain the homeostasis of nutrients and energy within the …

Advanced glycation end products in food and their effects on intestinal tract

C Nie, Y Li, H Qian, H Ying, L Wang - Critical Reviews in Food …, 2022 - Taylor & Francis
With the development of living standards, harmful substances in diet and food safety have
seriously endangered people health and life. Advanced glycation end products (AGEs) …

Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex

S Strickson, KF Houslay, VA Negri… - European …, 2023 - Eur Respiratory Soc
Background Epithelial damage, repair and remodelling are critical features of chronic airway
diseases including chronic obstructive pulmonary disease (COPD). Interleukin (IL)-33 …

Reactive oxygen species and antioxidative defense in chronic obstructive pulmonary disease

A Taniguchi, M Tsuge, N Miyahara, H Tsukahara - Antioxidants, 2021 - mdpi.com
The respiratory system is continuously exposed to endogenous and exogenous oxidants.
Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation of …

The role of HMGB1/RAGE/TLR4 signaling pathways in cigarette smoke‐induced inflammation in chronic obstructive pulmonary disease

L Lin, J Li, Q Song, W Cheng… - … inflammation and disease, 2022 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a common chronic respiratory disease
with irreversible and continuous progression. It has become the fifth most burdensome …

Copper stress shapes the dynamic behavior of amoebae and their associated bacteria

Y Shi, L Ma, M Zhou, Z He, Y Zhao, J Hong… - The ISME …, 2024 - academic.oup.com
Amoeba-bacteria interactions are prevalent in both natural ecosystems and engineered
environments. Amoebae, as essential consumers, hold significant ecological importance …

TCMFP: a novel herbal formula prediction method based on network target's score integrated with semi-supervised learning genetic algorithms

Q Niu, H Li, L Tong, S Liu, W Zong… - Briefings in …, 2023 - academic.oup.com
Traditional Chinese medicine (TCM) has accumulated thousands years of knowledge in
herbal therapy, but the use of herbal formulas is still characterized by reliance on personal …

RAGE signaling during tobacco smoke-induced lung inflammation and potential therapeutic utility of SAGEs

KM Hirschi-Budge, KYF Tsai, KL Curtis… - BMC Pulmonary …, 2022 - Springer
Background Smoke exposure culminates as a progressive lung complication involving
airway inflammation and remodeling. While primary smoke poses the greatest risk, nearly …

[HTML][HTML] Transcriptomic and proteomic investigation of the ameliorative effect of total polyphenolic glycoside extract on hepatic fibrosis in Lamiophlomis rotata Kudo via …

C Yang, X Geng, G Wan, L Song, Y Wang… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance During the regression of liver fibrosis, a decrease in
hepatic stellate cells (HSCs) can occur through apoptosis or inactivation of activated HSCs …