Current trends in computer aided drug design and a highlight of drugs discovered via computational techniques: A review
VT Sabe, T Ntombela, LA Jhamba… - European Journal of …, 2021 - Elsevier
Computer-aided drug design (CADD) is one of the pivotal approaches to contemporary pre-
clinical drug discovery, and various computational techniques and software programs are …
clinical drug discovery, and various computational techniques and software programs are …
[HTML][HTML] Fungal mushrooms: a natural compound with therapeutic applications
Fungi are extremely diverse in terms of morphology, ecology, metabolism, and phylogeny.
Approximately, 130 medicinal activities like antitumor, immunomodulation, antioxidant …
Approximately, 130 medicinal activities like antitumor, immunomodulation, antioxidant …
[HTML][HTML] Advanced methods for natural products discovery: bioactivity screening, dereplication, metabolomics profiling, genomic sequencing, databases and informatic …
Natural Products (NP) are essential for the discovery of novel drugs and products for
numerous biotechnological applications. The NP discovery process is expensive and time …
numerous biotechnological applications. The NP discovery process is expensive and time …
[HTML][HTML] From traditional ethnopharmacology to modern natural drug discovery: A methodology discussion and specific examples
S Pirintsos, A Panagiotopoulos, M Bariotakis… - Molecules, 2022 - mdpi.com
Ethnopharmacology, through the description of the beneficial effects of plants, has provided
an early framework for the therapeutic use of natural compounds. Natural products, either in …
an early framework for the therapeutic use of natural compounds. Natural products, either in …
[HTML][HTML] A systematic review of computational approaches to understand cancer biology for informed drug repurposing
Cancer is the second leading cause of death globally, trailing only heart disease. In the
United States alone, 1.9 million new cancer cases and 609,360 deaths were recorded for …
United States alone, 1.9 million new cancer cases and 609,360 deaths were recorded for …
Intermolecular interactions between nitrosourea and polyoxometalate compounds
Herein, the aim of this work was to investigate the intermolecular interactions between
polyoxometalate (POMs) as a drug‐delivery system with nitrosourea at different sites: CH3 …
polyoxometalate (POMs) as a drug‐delivery system with nitrosourea at different sites: CH3 …
From lock-in to transformation: A path-centric theory of emerging technology and organizing
We offer a path-centric theory of emerging technology and organizing that addresses a basic
question. When does emerging technology lead to transformative change? A path-centric …
question. When does emerging technology lead to transformative change? A path-centric …
How far have we explored fungi to fight cancer?
The use of fungal cultures have been well documented in human history. Although its used
in healthcare, like penicillin and statins, have saved countless of lives, but there is still no …
in healthcare, like penicillin and statins, have saved countless of lives, but there is still no …
The new era of drug discovery: The power of computer-aided drug design (CADD)
IJS Nascimento, TM de Aquino… - Letters in Drug …, 2022 - ingentaconnect.com
Drug design and discovery is a process that requires high financial costs and is
timeconsuming. For many years, this process focused on empirical pharmacology. However …
timeconsuming. For many years, this process focused on empirical pharmacology. However …
[HTML][HTML] Novel 1, 3-thiazole analogues with potent activity against breast cancer: A design, synthesis, in vitro, and in silico study
MG Salem, DMA El-Maaty, YIM El-Deen, BH Elesawy… - Molecules, 2022 - mdpi.com
Breast cancer is the most common cancer in women, responsible for over half a million
deaths in 2020. Almost 75% of FDA-approved drugs are mainly nitrogen-and sulfur …
deaths in 2020. Almost 75% of FDA-approved drugs are mainly nitrogen-and sulfur …