Background: Despite its lengthy history, the study of jaundice, hyperbilirubinemia and
kernicterus suffers from a lack of clarity and consistency in the key terms used to describe …

Phototherapy is universally recognized as the first option for treating neonatal jaundice due
to its unparalleled efficiency and safety in reducing the high serum free bilirubin levels and …

Bilirubin is the end product of heme catabolism formed during a process that involves
oxidation-reduction reactions and conserves iron body stores. Unconjugated …

Despite the availability of successful prevention strategies to prevent excessive
hyperbilirubinemia, the neurological sequelae of bilirubin neurotoxicity (BNTx) still occur …

Objective To compare the association of unbound bilirubin (UB), total serum bilirubin (TSB),
and bilirubin: albumin molar ratio (BAMR) with acute bilirubin encephalopathy (ABE), as …

Bilirubin-induced brain injury in the neonatal period has detrimental effects on
neurodevelopment that persist into childhood and adulthood, contributing to childhood …

Objective This study evaluates whether unbound bilirubin is a better predictor of auditory
neuropathy spectrum disorder (ANSD) than total serum bilirubin (TSB) or the bilirubin …

The primary goal of the evaluation and management of unconjugated hyperbilirubinemia in
premature infants is to prevent acute and chronic bilirubin-induced neurotoxicity, a spectrum …

Apnoea of prematurity (AOP) affects almost all infants born at< 28 weeks gestation or with
birth weight< 1000 g. When untreated, AOP may be associated with negative outcomes …

Background Although it is known that unbound bilirubin can enter the brain, there is little
evidence of its association with the development of acute bilirubin encephalopathy. Here …