Heart failure with preserved ejection fraction in perspective
MA Pfeffer, AM Shah, BA Borlaug - Circulation research, 2019 - Am Heart Assoc
Approximately half of the patients with signs and symptoms of heart failure have a left
ventricular ejection fraction that is not markedly abnormal. Despite the historically initial …
ventricular ejection fraction that is not markedly abnormal. Despite the historically initial …
The pathophysiology of heart failure with preserved ejection fraction
BA Borlaug - Nature Reviews Cardiology, 2014 - nature.com
Approximately half of all patients with heart failure have preserved ejection fraction (HFpEF)
and, as life expectancies continue to increase in western societies, the prevalence of HFpEF …
and, as life expectancies continue to increase in western societies, the prevalence of HFpEF …
2016 focused update: clinical recommendations for cardiopulmonary exercise testing data assessment in specific patient populations
In the past several decades, cardiopulmonary exercise testing (CPX) has seen an
exponential increase in its evidence base. The growing volume of evidence in support of …
exponential increase in its evidence base. The growing volume of evidence in support of …
Right heart dysfunction in heart failure with preserved ejection fraction
V Melenovsky, SJ Hwang, G Lin… - European heart …, 2014 - academic.oup.com
Aim Right heart function is not well characterized in patients with heart failure and preserved
ejection fraction (HFpEF). The goal of this study was to examine the haemodynamic, clinical …
ejection fraction (HFpEF). The goal of this study was to examine the haemodynamic, clinical …
Pulmonary hypertension in heart failure: pathophysiology, pathobiology, and emerging clinical perspectives
M Guazzi, R Naeije - Journal of the American College of Cardiology, 2017 - jacc.org
Pulmonary hypertension is a common hemodynamic complication of heart failure. Interest in
left-sided pulmonary hypertension has increased remarkably in recent years because its …
left-sided pulmonary hypertension has increased remarkably in recent years because its …
Pulmonary hypertension due to left heart diseases
JL Vachiéry, Y Adir, JA Barberà, H Champion… - Journal of the American …, 2013 - jacc.org
Pulmonary hypertension (PH), a common complication of left heart diseases (LHD),
negatively impacts symptoms, exercise capacity, and outcome. Although the true prevalence …
negatively impacts symptoms, exercise capacity, and outcome. Although the true prevalence …
Left atrial remodeling and function in advanced heart failure with preserved or reduced ejection fraction
V Melenovsky, SJ Hwang, MM Redfield… - Circulation: Heart …, 2015 - Am Heart Assoc
Background—Left atrial (LA) structure and function are altered in most heart failure (HF)
patients, but there may be fundamental differences in LA properties between HF with …
patients, but there may be fundamental differences in LA properties between HF with …
Abnormal right ventricular-pulmonary artery coupling with exercise in heart failure with preserved ejection fraction
BA Borlaug, GC Kane, V Melenovsky… - European heart …, 2016 - academic.oup.com
Background Exercise intolerance is common in people with heart failure and preserved
ejection fraction (HFpEF). Right ventricular (RV) dysfunction has been shown at rest in …
ejection fraction (HFpEF). Right ventricular (RV) dysfunction has been shown at rest in …
Tricuspid annular plane systolic excursion and pulmonary arterial systolic pressure relationship in heart failure: an index of right ventricular contractile function and …
M Guazzi, F Bandera, G Pelissero… - American Journal …, 2013 - journals.physiology.org
Echo-derived pulmonary arterial systolic pressure (PASP) and right ventricular (RV) tricuspid
annular plane systolic excursion (TAPSE; from the end of diastole to end-systole) are of …
annular plane systolic excursion (TAPSE; from the end of diastole to end-systole) are of …
New strategies for heart failure with preserved ejection fraction: the importance of targeted therapies for heart failure phenotypes
The management of heart failure with reduced ejection fraction (HF-REF) has improved
significantly over the last two decades. In contrast, little or no progress has been made in …
significantly over the last two decades. In contrast, little or no progress has been made in …