[HTML][HTML] Recent progress in treatment of hepatocellular carcinoma

Z Chen, H Xie, M Hu, T Huang, Y Hu… - American journal of …, 2020 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related death
worldwide. In the past decade, there have been improvements in non-drug therapies and …

Immune checkpoint inhibitors in the treatment of HCC

C Donisi, M Puzzoni, P Ziranu, E Lai, S Mariani… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is the typical inflammation-induced neoplasia. It often
prospers where a chronic liver disease persists, thus leading a strong rationale for immune …

Comparative efficacy of atezolizumab plus bevacizumab and other treatment options for patients with unresectable hepatocellular carcinoma: a network meta-analysis

A Vogel, L Rimassa, HC Sun, GK Abou-Alfa… - Liver Cancer, 2021 - karger.com
Background: Most phase 3 clinical trials of systemic therapy for first-line unresectable
hepatocellular carcinoma (HCC) have failed, with the exception of SHARP, REFLECT, and …

REal life study of LEnVAtiNib therapy for HepAtocellular carcinoma: RELEVANT study

A Casadei-Gardini, M Rimini, M Kudo, S Shimose… - Liver Cancer, 2022 - karger.com
Introduction: In the REFLECT trial, lenvatinib was found to be noninferior compared to
sorafenib in terms of overall survival. Here, we analyze the effects of lenvatinib in the real-life …

Lenvatinib versus Sorafenib as first‐line treatment in hepatocellular carcinoma: a multi‐institutional matched case‐control study

M Rimini, S Shimose, S Lonardi, T Tada… - Hepatology …, 2021 - Wiley Online Library
Abstract Background Advanced Hepatocarcinoma (HCC) is an important health problem
worldwide. Recently, the REFLECT trial demonstrated the non‐inferiority of Lenvatinib …

Safety and efficacy of lenvatinib combined with camrelizumab plus transcatheter arterial chemoembolization for unresectable hepatocellular carcinoma: A two-center …

B Sun, L Zhang, T Sun, Y Ren, Y Cao, W Zhang… - Frontiers in …, 2022 - frontiersin.org
Objectives To compare the safety and efficacy of lenvatinib (LEN) combined with
camrelizumab plus transcatheter arterial chemoembolization (TACE-LEN-C) and TACE …

[HTML][HTML] Efficacy and safety of lenvatinib for patients with advanced hepatocellular carcinoma: a retrospective, real-world study conducted in China

DX Wang, X Yang, JZ Lin, Y Bai, JY Long… - World journal of …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Lenvatinib has become an indispensable part of treatment regimens for
patients with advanced hepatocellular carcinoma (aHCC). Several recent real-world studies …

FGF/FGFR signaling in hepatocellular carcinoma: from carcinogenesis to recent therapeutic intervention

Y Wang, D Liu, T Zhang, L Xia - Cancers, 2021 - mdpi.com
Simple Summary As the most common primary liver cancer, HCC is a tricky cancer resistant
to systemic therapies. The fibroblast growth factor family and its receptors are gaining more …

Introducing immunotherapy for advanced hepatocellular carcinoma patients: Too early or too fast?

E Lai, G Astara, P Ziranu, A Pretta, M Migliari… - Critical Reviews in …, 2021 - Elsevier
Advanced hepatocellular carcinoma (HCC) is the most frequent liver cancer. Immunotherapy
has been explored in this disease in order to improve survival outcomes. Nowadays …

Similar efficacy and safety between lenvatinib versus atezolizumab plus bevacizumab as the first‐line treatment for unresectable hepatocellular carcinoma

CW Su, W Teng, PT Lin, WJ Jeng, KA Chen… - Cancer …, 2023 - Wiley Online Library
Background Lenvatinib and atezolizumab plus bevacizumab (A+ B) have been used for
unresectable hepatocellular carcinoma (HCC) as first‐line therapy. Real‐world studies …