Cell‐surface central nervous system autoantibodies: clinical relevance and emerging paradigms

SR Irani, JM Gelfand, A Al‐Diwani… - Annals of …, 2014 - Wiley Online Library
The recent discovery of several potentially pathogenic autoantibodies has helped identify
patients with clinically distinctive central nervous system diseases that appear to benefit from …

Immunity and inflammation in status epilepticus and its sequelae: possibilities for therapeutic application

A Vezzani, R Dingledine… - Expert review of …, 2015 - Taylor & Francis
Status epilepticus (SE) is a life-threatening neurological emergency often refractory to
available treatment options. It is a very heterogeneous condition in terms of clinical …

Autoimmune epilepsy: clinical characteristics and response to immunotherapy

AML Quek, JW Britton, A McKeon, E So… - Archives of …, 2012 - jamanetwork.com
Objective To describe clinical characteristics and immunotherapy responses in patients with
autoimmune epilepsy. Design Observational, retrospective case series. Setting Mayo Clinic …

Prevalence of neurologic autoantibodies in cohorts of patients with new and established epilepsy

T Brenner, GJ Sills, Y Hart, S Howell, P Waters… - …, 2013 - Wiley Online Library
Purpose Autoantibodies to specific neurologic proteins are associated with subacute onset
encephalopathies, which often present with seizures that are poorly controlled by …

Microglial phenotypes in the human epileptic temporal lobe

M Morin-Brureau, G Milior, J Royer, F Chali… - Brain, 2018 - academic.oup.com
Microglia, the immune cells of the brain, are highly plastic and possess multiple functional
phenotypes. Differences in phenotype in different regions and different states of epileptic …

[HTML][HTML] Outcome of limbic encephalitis with VGKC-complex antibodies: relation to antigenic specificity

MP Malter, C Frisch, JC Schoene-Bake… - Journal of …, 2014 - Springer
In limbic encephalitis (LE) with antibodies (Abs) to the voltage-gated potassium channel
complex (VGKC), the Abs are mainly directed to the VGKC-complex proteins, leucine-rich …

[HTML][HTML] The autoantibody-mediated encephalitides: from clinical observations to molecular pathogenesis

S Ramanathan, A Al-Diwani, P Waters, SR Irani - Journal of Neurology, 2021 - Springer
The autoimmune encephalitis (AE) syndromes have been characterised by the detection of
autoantibodies in serum and/or cerebrospinal fluid which target the extracellular domains of …

Clinical manifestations and outcomes of the treatment of patients with GABAB encephalitis

TJ Kim, ST Lee, JW Shin, J Moon, JA Lim… - Journal of …, 2014 - Elsevier
Encephalitis associated with anti-γ-aminobutyric acid-B (GABA B) receptor antibodies has
been identified recently. However, only a few cases have been reported to date and its …

Current and emerging pharmacotherapy for the treatment of Lennox-Gastaut syndrome

FMC Besag, MJ Vasey, RFM Chin - Expert Opinion on …, 2023 - Taylor & Francis
ABSTRACT Introduction Lennox-Gastaut syndrome (LGS) is a severe childhood-onset
epileptic encephalopathy, characterized by multiple seizure types, generalized slow spike …

[HTML][HTML] Febrile infection-related epilepsy syndrome: a study of 12 patients

RH Caraballo, G Reyes, MFL Avaria, MC Buompadre… - Seizure, 2013 - Elsevier
Purpose To analyze the electroclinical features, neuroimaging findings, treatment, and
outcome of 12 patients with febrile infection-related epilepsy syndrome (FIRES). Methods …