Adult-onset temporal lobe epilepsy suspicious for autoimmune pathogenesis: Autoantibody prevalence and clinical correlates
JC Kuehn, C Meschede, C Helmstaedter, R Surges… - PLoS …, 2020 - journals.plos.org
Temporal lobe adult-onset seizures (TAOS) related to autoimmunity represent an
increasingly recognized disease syndrome within the spectrum of epilepsies. In this context …
increasingly recognized disease syndrome within the spectrum of epilepsies. In this context …
The Kv1-associated molecules TAG-1 and Caspr2 are selectively targeted to the axon initial segment in hippocampal neurons
D Pinatel, B Hivert, M Saint-Martin… - Journal of Cell …, 2017 - journals.biologists.com
ABSTRACT Caspr2 and TAG-1 (also known as CNTNAP2 and CNTN2, respectively) are cell
adhesion molecules (CAMs) associated with the voltage-gated potassium channels Kv1. 1 …
adhesion molecules (CAMs) associated with the voltage-gated potassium channels Kv1. 1 …
Immunological perspectives of temporal lobe seizures
S Liimatainen, K Lehtimäki, J Palmio, T Alapirtti… - Journal of …, 2013 - Elsevier
The temporal lobes are affected in many different neurological disorders, such as
neurodegenerative diseases, viral and immunological encephalitides, and epilepsy. Both …
neurodegenerative diseases, viral and immunological encephalitides, and epilepsy. Both …
Differential distribution of voltage-gated ion channels in cortical neurons: implications for epilepsy
ND Child, EE Benarroch - Neurology, 2014 - AAN Enterprises
Neurons contain different functional somatodendritic and axonal domains, each with a
characteristic distribution of voltage-gated ion channels, synaptic inputs, and function. The …
characteristic distribution of voltage-gated ion channels, synaptic inputs, and function. The …
Anti-N-methyl-D-aspartate receptor (NMDAR) antibody encephalitis presents in atypical types and coexists with neuromyelitis optica spectrum disorder or …
K Qin, W Wu, Y Huang, D Xu, L Zhang, B Zheng… - BMC neurology, 2017 - Springer
Abstract Background Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a
clinically heterogeneous disorder characterized by epileptic seizures, psychosis, dyskinesia …
clinically heterogeneous disorder characterized by epileptic seizures, psychosis, dyskinesia …
The search for circulating epilepsy biomarkers
M Hegde, DH Lowenstein - Biomarkers in medicine, 2014 - Taylor & Francis
Few would experience greater benefit from the development of biomarkers than those who
suffer from epilepsy. Both the timing of individual seizures and the overall course of the …
suffer from epilepsy. Both the timing of individual seizures and the overall course of the …
Typical clinical and imaging manifestations of encephalitis with anti-γ-aminobutyric acid B receptor antibodies: clinical experience and a literature review
Z Si, A Wang, J Liu, Z Zhang, K Hu - Neurological Sciences, 2019 - Springer
Objective To explore the clinical, imaging, and electroencephalogram (EEG) findings, as
well as the treatment and prognosis of five patients with anti-γ-aminobutyric acid B receptor …
well as the treatment and prognosis of five patients with anti-γ-aminobutyric acid B receptor …
Advancing the management of childhood epilepsies
JH Cross, G Kluger, L Lagae - european journal of paediatric neurology, 2013 - Elsevier
Childhood epilepsies comprise a heterogeneous group of disorders and syndromes that
vary in terms of severity, prognosis and treatment requirements. Effective management …
vary in terms of severity, prognosis and treatment requirements. Effective management …
[HTML][HTML] The expanding spectrum of clinically-distinctive, immunotherapy-responsive autoimmune encephalopathies
The autoimmune encephalopathies are a group of conditions that are associated with
autoantibodies against surface neuronal proteins, which are likely to mediate the disease …
autoantibodies against surface neuronal proteins, which are likely to mediate the disease …