Breath analysis: potential for clinical diagnosis and exposure assessment

W Cao, Y Duan - Clinical chemistry, 2006 - academic.oup.com
Breath tests are among the least invasive methods available for clinical diagnosis, disease
state monitoring, and environmental exposure assessment. In recent years, interest in breath …

Exhaled biomarkers in lung cancer

I Horvath, Z Lazar, N Gyulai, M Kollai… - European Respiratory …, 2009 - Eur Respiratory Soc
Lung cancer is the leading cause of cancer death. Results of therapeutic interventions are
particularly discouraging when the disease is discovered in an advanced stage. Early …

Exhaled breath condensate: methodological recommendations and unresolved questions

I Horváth, J Hunt, PJ Barnes - European Respiratory Journal, 2005 - Eur Respiratory Soc
Collection of exhaled breath condensate (EBC) is a noninvasive method for obtaining
samples from the lungs. EBC contains large number of mediators including adenosine …

Oxidative stress in pathogenesis of chronic obstructive pulmonary disease: cellular and molecular mechanisms

I Rahman - Cell biochemistry and biophysics, 2005 - Springer
Chronic obstructive pulmonary disease (COPD) is a slowly progressive condition
characterized by airflow limitation, which is largely irreversible. Oxidative stress and …

Highly reactive oxygen species: detection, formation, and possible functions

W Freinbichler, MA Colivicchi, C Stefanini… - Cellular and molecular …, 2011 - Springer
The so-called reactive oxygen species (ROS) are defined as oxygen-containing species that
are more reactive than O 2 itself, which include hydrogen peroxide and superoxide …

Biomarkers of oxidative stress and DNA damage in agricultural workers: a pilot study

JF Muniz, L McCauley, J Scherer, M Lasarev… - Toxicology and applied …, 2008 - Elsevier
Oxidative stress and DNA damage have been proposed as mechanisms linking pesticide
exposure to health effects such as cancer and neurological diseases. A study of pesticide …

The role of oxidative stress in the pathogenesis of COPD: implications for therapy

I Rahman - Treatments in respiratory medicine, 2005 - Springer
Chronic inflammation and oxidative stress are important features in the pathogenesis of
COPD. The increased oxidative stress in patients with COPD is the result of an increased …

Exhaled metallic elements and serum pneumoproteins in asymptomatic smokers and patients with COPD or asthma

A Mutti, M Corradi, M Goldoni, MV Vettori, A Bernard… - Chest, 2006 - Elsevier
Study objectives The aim of this study was to characterize the elemental composition of
exhaled breath condensate (EBC) in order to identify new biomarkers of exposure and …

Antioxidant therapeutic advances in COPD

I Rahman - Therapeutic advances in respiratory disease, 2008 - journals.sagepub.com
Chronic obstructive pulmonary disease (COPD) is associated with a high incidence of
morbidity and mortality. Cigarette smoke-induced oxidative stress is intimately associated …

Standardization procedures for real-time breath analysis by secondary electrospray ionization high-resolution mass spectrometry

KD Singh, G Tancev, F Decrue, J Usemann… - Analytical and …, 2019 - Springer
Despite the attractiveness of breath analysis as a non-invasive means to retrieve relevant
metabolic information, its introduction into routine clinical practice remains a challenge …