The roles of serotonin in neuropsychiatric disorders

M Pourhamzeh, FG Moravej, M Arabi… - Cellular and molecular …, 2022 - Springer
The serotonergic system extends throughout the central nervous system (CNS) and the
gastrointestinal (GI) tract. In the CNS, serotonin (5-HT, 5-hydroxytryptamine) modulates a …

The body comes first. Embodied reparation and the co-creation of infant bodily-self

R Montirosso, F McGlone - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
During infancy relational experiences of body-to-body exchanges (ie, embodied
interactions) contribute to the infant's bodily perception. Early embodied interactions are …

SARS-CoV-2 airway infection results in the development of somatosensory abnormalities in a hamster model

RA Serafini, JJ Frere, J Zimering, IM Giosan… - Science …, 2023 - science.org
Although largely confined to the airways, SARS-CoV-2 infection has been associated with
sensory abnormalities that manifest in both acute and chronic phenotypes. To gain insight …

[HTML][HTML] Hidden pandemic: COVID-19-related stress, SLC6A4 methylation, and infants' temperament at 3 months

L Provenzi, F Mambretti, M Villa, S Grumi, A Citterio… - Scientific Reports, 2021 - nature.com
The COVID-19 pandemic represents a collective trauma that may have enduring stress
effects during sensitive periods, such as pregnancy. Prenatal stress may result in epigenetic …

[HTML][HTML] Targeting small GTPases: emerging grasps on previously untamable targets, pioneered by KRAS

G Yin, J Huang, J Petela, H Jiang, Y Zhang… - Signal transduction and …, 2023 - nature.com
Abstract Small GTPases including Ras, Rho, Rab, Arf, and Ran are omnipresent molecular
switches in regulating key cellular functions. Their dysregulation is a therapeutic target for …

Cumulative procedural pain and brain development in very preterm infants: A systematic review of clinical and preclinical studies

T Boggini, S Pozzoli, P Schiavolin, R Erario… - Neuroscience & …, 2021 - Elsevier
Very preterm infants may manifest neurodevelopmental impairments, even in the absence of
brain lesions. Pathogenesis is complex and multifactorial. Evidence suggests a role of early …

Measuring the Outcomes of Maternal COVID-19-related Prenatal Exposure (MOM-COPE): study protocol for a multicentric longitudinal project

L Provenzi, S Grumi, R Giorda, G Biasucci, R Bonini… - BMJ open, 2020 - bmjopen.bmj.com
Introduction COVID-19 is a highly infectious respiratory disease that rapidly emerged as an
unprecedented epidemic in Europe, with a primary hotspot in Northern Italy during the first …

Epigenetic protection: maternal touch and DNA-methylation in early life

ILCM Wigley, E Mascheroni, S Bonichini… - Current Opinion in …, 2022 - Elsevier
Highlights•Epigenetics links individual experiences and later-life behavioral
phenotypes.•Affective touch is a key experience in infant development.•Early mother-infant …

The consequences of neonatal pain, stress and opiate administration in animal models: An extensive meta-analysis concerning neuronal cell death, motor and …

P Steinbauer, FJ Monje, O Kothgassner… - Neuroscience & …, 2022 - Elsevier
This systematic review and meta-analysis aimed to investigate the association of neonatal
exposure to pain, stress, opiate administration alone, as well as opiate administration prior …

Prenatal exposure to environmental air pollution and psychosocial stress jointly contribute to the epigenetic regulation of the serotonin transporter gene in newborns

S Nazzari, L Cagliero, S Grumi, E Pisoni… - Molecular …, 2023 - nature.com
Antenatal exposures to maternal stress and to particulate matter with an aerodynamic
diameter of less than 2.5 μm (PM2. 5) have been independently associated with …