Axial Spondyloarthritis: Evolving concepts regarding the disease's diagnosis and treatment
AA Drosos, AI Venetsanopoulou, PV Voulgari - European Journal of Internal …, 2023 - Elsevier
Spondyloarthritis (SpA) is a chronic inflammatory disease that affects the axial skeleton
(axSpA) and/or the peripheral joints (p-SpA) and entheses. The natural history of SpA in the …
(axSpA) and/or the peripheral joints (p-SpA) and entheses. The natural history of SpA in the …
Bone formation in ankylosing spondylitis during anti-tumour necrosis factor therapy imaged by 18F-fluoride positron emission tomography
STG Bruijnen, NJF Verweij… - …, 2018 - academic.oup.com
Objectives Excessive bone formation is an important hallmark of AS. Recently it has been
demonstrated that axial bony lesions in AS patients can be visualized using 18F-fluoride …
demonstrated that axial bony lesions in AS patients can be visualized using 18F-fluoride …
[HTML][HTML] Exploring causal correlations between inflammatory cytokines and ankylosing spondylitis: a bidirectional mendelian-randomization study
P Fang, X Liu, Y Qiu, Y Wang, D Wang, J Zhao… - Frontiers in …, 2023 - frontiersin.org
Background The impact of inflammatory factors on the development of Ankylosing
Spondylitis (AS) is widely recognized, but the exact causal relationship remains unclear …
Spondylitis (AS) is widely recognized, but the exact causal relationship remains unclear …
Knowledge mapping of biological disease-modifying anti-rheumatic drugs for axial spondyloarthritis: a bibliometric study
Q He, J Chen, X Yu, J Liao, Z Huang, J Yang… - Clinical …, 2023 - Springer
Various biological disease-modifying anti-rheumatic drugs (bDMARDs) have been applied
for treating axial spondyloarthritis (axSpA). However, there is a glaring absence of a …
for treating axial spondyloarthritis (axSpA). However, there is a glaring absence of a …
[HTML][HTML] Serum granulocyte-macrophage colony-stimulating factor (GM-CSF) is increased in patients with active radiographic axial spondyloarthritis and persists …
C Papagoras, S Tsiami, A Chrysanthopoulou… - Arthritis Research & …, 2022 - Springer
Background Accumulating evidence supports the role of monocytes and neutrophils in
radiographic axSpA (r-axSpA). Granulocyte-macrophage colony-stimulating factor (GM …
radiographic axSpA (r-axSpA). Granulocyte-macrophage colony-stimulating factor (GM …
[HTML][HTML] MYC promotes fibroblast osteogenesis by regulating ALP and BMP2 to participate in ectopic ossification of ankylosing spondylitis
Q Jin, Y Liu, Z Zhang, X Wen, Z Chen, H Tian… - Arthritis Research & …, 2023 - Springer
Background Ectopic ossification is an important cause of disability in patients with
ankylosing spondylitis (AS). Whether fibroblasts can transdifferentiate into osteoblasts and …
ankylosing spondylitis (AS). Whether fibroblasts can transdifferentiate into osteoblasts and …
DNA methylation of DKK‐1 may correlate with pathological bone formation in ankylosing spondylitis
YC Zou, ZJ Wang, LC Shao, ZH Xia… - Immunity …, 2023 - Wiley Online Library
Objective To investigate DNA methylation (DNAm) status of dickkopf‐associated protein 1
(DKK‐1) in ossified hip capsule synovium and serum among patients with ankylosing …
(DKK‐1) in ossified hip capsule synovium and serum among patients with ankylosing …
Efficacy and NSAID-sparing effect of secukinumab 150 mg in ankylosing spondylitis: results from phase IV ASTRUM study
U Kiltz, X Baraliakos, J Brandt-Jürgens… - Therapeutic …, 2024 - journals.sagepub.com
Background: Radiographic axial spondyloarthritis (r-axSpA), formerly known as ankylosing
spondylitis (AS), is a chronic, inflammatory rheumatic disease associated with symptoms …
spondylitis (AS), is a chronic, inflammatory rheumatic disease associated with symptoms …
[HTML][HTML] Molecular mechanisms of AMPK/YAP/NLRP3 signaling pathway affecting the occurrence and development of ankylosing spondylitis
R Fu, X Guo, Z Pan, Y Wang, J Xu, L Zhang… - Journal of Orthopaedic …, 2023 - Springer
Background Investigate the AMPK (protein kinase AMP-activated catalytic subunit alpha
1)/YAP (Yes1 associated transcriptional regulator)/NLRP3 (NLR family pyrin domain …
1)/YAP (Yes1 associated transcriptional regulator)/NLRP3 (NLR family pyrin domain …
[HTML][HTML] Interaction effects of significant risk factors on low bone mineral density in ankylosing spondylitis
W Sun, W Mu, C Jefferies, T Learch, M Ishimori, J Wu… - PeerJ, 2023 - peerj.com
Background To analyze individually and interactively critical risk factors, which are closely
related to low bone mineral density (BMD) in patient with ankylosing spondylitis (AS) …
related to low bone mineral density (BMD) in patient with ankylosing spondylitis (AS) …