When facing an acute viral infection, our immune systems need to function with finite
precision to enable the elimination of the pathogen, whilst protecting our bodies from …

Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening state of immune
hyperactivation that arises in the setting of genetic mutations and infectious, inflammatory, or …

Abstract Purpose of Review Coronavirus disease 2019 (COVID-19) has been the cause of
significant global morbidity and mortality. Here, we review the literature to date of the short …

Objective: This study aimed to assess the role of Tocilizumab therapy (TCZ) in terms of ICU
admission and mortality rate of critically ill patients with severe COVID-19 pneumonia …

Objectives To investigate the clinical significance of numeric and morphologic peripheral
blood (PB) changes in coronavirus disease 2019 (COVID-19)–positive patients in predicting …

Context.—Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening disorder of
immune regulation that can eventually result in end-organ damage and death. HLH is …

A hyperinflammatory 'cytokine storm'state termed macrophage activation syndrome (MAS),
culminating from a complex interplay of genetics, immunodeficiency, infectious triggers and …

Visceral Leishmaniasis (VL) is a vector-borne disease caused by an intracellular protozoa of
the genus Leishmania that can be lethal if not treated. VL is caused by Leishmania donovani …

Objectives A subset of coronavirus disease 2019 (COVID-19) patients exhibit clinical
features of cytokine storm. However, clinicopathologic features diagnostic of …

Multicentric Castleman's disease (MCD) describes a heterogeneous group of disorders
involving proliferation of morphologically benign lymphocytes due to excessive …