Abstract Individuals with 5α-reductase-2 deficiency (5α-RD-2) and 17β-hydroxysteroid
dehydrogenase-3 deficiency (17β-HSD-3) are often raised as girls. Over the past number of …

Abstract Introduction Disorders of Sex Development (DSD) are a wide range of congenital
conditions characterized by an incongruence of components involved in sexual …

Defects in the conversion of androstenedione to testosterone in the fetal testes by the
enzyme 17β–hydroxysteroid dehydrogenase (17β–HSD) give rise to genetic males with …

17β-Hydroxysteroid dehydrogenase-3 (17βHSD3) deficiency is an autosomal recessive
form of male pseudohermaphroditism caused by mutations in the HSD17B3 gene. In a …

Role of Androgens in Male Gender Role Behavior | Endocrine Reviews | Oxford Academic
Skip to Main Content Advertisement Oxford Academic Journals Books Search Menu …

17β-Hydroxysteroid dehydrogenases (17β-HSDs) are enzymes involved in both the
activation and inactivation of androgens and estrogens. 17β-HSD type 1 shows a high …

Physical, sensory, and mental impairments can influence an individual's status in society as
much as the more familiar categories of gender, class, religion, race, and ethnicity. This was …

β-hydroxysteroid dehydrogenase type 3 (17βHSD-3) deficiency is a rare, but frequently
misdiagnosed autosomal recessive cause of 46, XY disorder of sex development (DSD) …

Objective 17β‐hydroxysteroid dehydrogenase type 3 isoenzyme (17β‐HSD3) is required to
produce testosterone for male sex differentiation. Mutations in the HSD17B3 gene cause …

Impairment of virilization in the male fetus (male pseudohermaphroditism) can result either
from de-creased testosterone formation or from impaired androgen metabolism or action …