Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic …

BB Aggarwal, KB Harikumar - The international journal of biochemistry & …, 2009 - Elsevier
Although safe in most cases, ancient treatments are ignored because neither their active
component nor their molecular targets are well defined. This is not the case, however, with …

[HTML][HTML] Extracellular vesicles: versatile nanomediators, potential biomarkers and therapeutic agents in atherosclerosis and COVID-19-related thrombosis

A Georgescu, M Simionescu - International journal of molecular sciences, 2021 - mdpi.com
Cells convey information among one another. One instrument employed to transmit data and
constituents to specific (target) cells is extracellular vesicles (EVs). They originate from a …

Invited review: Vascular cells contribute to atherosclerosis by cytokine-and innate-immunity-related inflammatory mechanisms

H Loppnow, K Werdan, M Buerke - Innate immunity, 2008 - journals.sagepub.com
Cardiovascular diseases are the human diseases with the highest death rate and
atherosclerosis is one of the major underlying causes of cardiovascular diseases …

[PDF][PDF] Clustering of cardiovascular risk factors in rheumatoid arthritis: the rationale for using statins

IF Gazi, DT Boumpas, DP Mikhailidis… - Clinical and …, 2007 - researchgate.net
Atherosclerosis may be more prevalent and more extensive in individuals with rheumatoid
arthritis (RA) compared with the general population. Despite the fact that traditional and …

[HTML][HTML] Therapeutic role of taurine as antioxidant in reducing hypertension risks in rats

MA Ibrahim, MM Eraqi, FA Alfaiz - Heliyon, 2020 - cell.com
Aim The current investigation focused on the therapeutic role of the administration of taurine
on hypertensive rats to reduce or cure the hazard effects of hypertension problems …

[HTML][HTML] Beneficial clinical effects of grape seed proanthocyanidin extract on the progression of carotid atherosclerotic plaques

AH Cao, J Wang, HQ Gao, P Zhang… - Journal of geriatric …, 2015 - ncbi.nlm.nih.gov
Background Atherosclerotic plaques indicate the occurrence of ischemia events and it is a
difficult task for clinical physicians. Grape seed proanthocyanidin extract (GSPE) has been …

Lipoprotein-associated phospholipase A2 and risk of carotid atherosclerosis and cardiovascular events in community-based older adults in China

C Wang, X Fang, Y Hua, Y Liu, Z Zhang, X Gu… - …, 2018 - journals.sagepub.com
We explored the associations between lipoprotein-associated phospholipase A2 (Lp-PLA2)
level and carotid atherosclerosis with all phenotypes and cardiovascular disease (CVD) …

Understanding the nutrigenomic definitions and concepts at the food–genome junction

MTR Subbiah - Omics A journal of integrative Biology, 2008 - liebertpub.com
The marked differences in individual response to dietary factors have led to major
controversies in nutrition and puzzled nutrition scientists over the last century. The emerging …

Numerical modeling of stress in stenotic arteries with microcalcifications: a micromechanical approximation

JF Wenk, P Papadopoulos, TI Zohdi - 2010 - asmedigitalcollection.asme.org
Most finite element models of atherosclerotic arteries do not account for the heterogeneity of
the plaque constituents at the microscale. Failure of plaque lesions has been shown to be a …

Chemical complexity and the genetics of aging

SD Pletcher, H Kabil, L Partridge - Annu. Rev. Ecol. Evol. Syst., 2007 - annualreviews.org
We examine how aging is influenced by various chemical challenges that organisms face
and by the molecular mechanisms that have evolved to modulate life span in response to …