Apoptotic pathways and Alzheimer's disease: probing therapeutic potential

VK Sharma, TG Singh, S Singh, N Garg… - Neurochemical …, 2021 - Springer
Apoptosis is an intrinsic biochemical, cellular process that regulates cell death and is crucial
for cell survival, cellular homeostasis, and maintaining the optimum functional status …

The ASD Living Biology: from cell proliferation to clinical phenotype

E Courchesne, T Pramparo, VH Gazestani… - Molecular …, 2019 - nature.com
Autism spectrum disorder (ASD) has captured the attention of scientists, clinicians and the
lay public because of its uncertain origins and striking and unexplained clinical …

Spatio-temporal regulation of circular RNA expression during porcine embryonic brain development

MT Venø, TB Hansen, ST Venø, BH Clausen… - Genome biology, 2015 - Springer
Background Recently, thousands of circular RNAs (circRNAs) have been discovered in
various tissues and cell types from human, mouse, fruit fly and nematodes. However …

Physiology and pharmacology of amyloid precursor protein

Y Cho, HG Bae, E Okun, TV Arumugam… - Pharmacology & …, 2022 - Elsevier
Amyloid precursor protein (APP) is an evolutionarily conserved transmembrane protein and
a well-characterized precursor protein of amyloid-beta (Aβ) peptides, which accumulate in …

[HTML][HTML] Use of human neuroblastoma SH-SY5Y cells to evaluate glyphosate-induced effects on oxidative stress, neuronal development and cell death signaling …

MA Martínez, JL Rodríguez, B Lopez-Torres… - Environment …, 2020 - Elsevier
Glyphosate-containing herbicides are the most used agrochemicals in the world. Their
indiscriminate application raises some concerns regarding the possible health and …

Effects of cannabidiol interactions with Wnt/β-catenin pathway and PPARγ on oxidative stress and neuroinflammation in Alzheimer's disease

A Vallée, Y Lecarpentier, R Guillevin… - Acta biochimica et …, 2017 - academic.oup.com
Alzheimer's disease (AD) is a neurodegenerative disease, in which the primary etiology
remains unknown. AD presents amyloid beta (Aβ) protein aggregation and neurofibrillary …

From nerve net to nerve ring, nerve cord and brain—evolution of the nervous system

D Arendt, MA Tosches, H Marlow - Nature Reviews Neuroscience, 2016 - nature.com
The puzzle of how complex nervous systems emerged remains unsolved. Comparative
studies of neurodevelopment in cnidarians and bilaterians suggest that this process began …

Wnt signaling in the nervous system and in Alzheimer's disease

NC Inestrosa, L Varela-Nallar - Journal of molecular cell biology, 2014 - academic.oup.com
Wnts comprise a large family of proteins that have shown to be part of a signaling cascade
that regulates several aspects of development including organogenesis, midbrain …

Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling

O Durak, F Gao, YJ Kaeser-Woo, R Rueda… - Nature …, 2016 - nature.com
De novo mutations in CHD8 are strongly associated with autism spectrum disorder, but the
basic biology of CHD8 remains poorly understood. Here we report that Chd8 knockdown …

The bovine herpesvirus 1 latency-reactivation cycle, a chronic problem in the cattle industry

JB Ostler, C Jones - Viruses, 2023 - mdpi.com
Bovine alphaherpesvirus 1 (BoHV-1) is a persistent and recurring disease that affects cattle
worldwide. It is a major contributor to bovine respiratory disease and reproductive failure in …