Apoptotic pathways and Alzheimer's disease: probing therapeutic potential
Apoptosis is an intrinsic biochemical, cellular process that regulates cell death and is crucial
for cell survival, cellular homeostasis, and maintaining the optimum functional status …
for cell survival, cellular homeostasis, and maintaining the optimum functional status …
The ASD Living Biology: from cell proliferation to clinical phenotype
E Courchesne, T Pramparo, VH Gazestani… - Molecular …, 2019 - nature.com
Autism spectrum disorder (ASD) has captured the attention of scientists, clinicians and the
lay public because of its uncertain origins and striking and unexplained clinical …
lay public because of its uncertain origins and striking and unexplained clinical …
Spatio-temporal regulation of circular RNA expression during porcine embryonic brain development
Background Recently, thousands of circular RNAs (circRNAs) have been discovered in
various tissues and cell types from human, mouse, fruit fly and nematodes. However …
various tissues and cell types from human, mouse, fruit fly and nematodes. However …
Physiology and pharmacology of amyloid precursor protein
Y Cho, HG Bae, E Okun, TV Arumugam… - Pharmacology & …, 2022 - Elsevier
Amyloid precursor protein (APP) is an evolutionarily conserved transmembrane protein and
a well-characterized precursor protein of amyloid-beta (Aβ) peptides, which accumulate in …
a well-characterized precursor protein of amyloid-beta (Aβ) peptides, which accumulate in …
[HTML][HTML] Use of human neuroblastoma SH-SY5Y cells to evaluate glyphosate-induced effects on oxidative stress, neuronal development and cell death signaling …
MA Martínez, JL Rodríguez, B Lopez-Torres… - Environment …, 2020 - Elsevier
Glyphosate-containing herbicides are the most used agrochemicals in the world. Their
indiscriminate application raises some concerns regarding the possible health and …
indiscriminate application raises some concerns regarding the possible health and …
Effects of cannabidiol interactions with Wnt/β-catenin pathway and PPARγ on oxidative stress and neuroinflammation in Alzheimer's disease
A Vallée, Y Lecarpentier, R Guillevin… - Acta biochimica et …, 2017 - academic.oup.com
Alzheimer's disease (AD) is a neurodegenerative disease, in which the primary etiology
remains unknown. AD presents amyloid beta (Aβ) protein aggregation and neurofibrillary …
remains unknown. AD presents amyloid beta (Aβ) protein aggregation and neurofibrillary …
From nerve net to nerve ring, nerve cord and brain—evolution of the nervous system
D Arendt, MA Tosches, H Marlow - Nature Reviews Neuroscience, 2016 - nature.com
The puzzle of how complex nervous systems emerged remains unsolved. Comparative
studies of neurodevelopment in cnidarians and bilaterians suggest that this process began …
studies of neurodevelopment in cnidarians and bilaterians suggest that this process began …
Wnt signaling in the nervous system and in Alzheimer's disease
NC Inestrosa, L Varela-Nallar - Journal of molecular cell biology, 2014 - academic.oup.com
Wnts comprise a large family of proteins that have shown to be part of a signaling cascade
that regulates several aspects of development including organogenesis, midbrain …
that regulates several aspects of development including organogenesis, midbrain …
Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling
De novo mutations in CHD8 are strongly associated with autism spectrum disorder, but the
basic biology of CHD8 remains poorly understood. Here we report that Chd8 knockdown …
basic biology of CHD8 remains poorly understood. Here we report that Chd8 knockdown …
The bovine herpesvirus 1 latency-reactivation cycle, a chronic problem in the cattle industry
JB Ostler, C Jones - Viruses, 2023 - mdpi.com
Bovine alphaherpesvirus 1 (BoHV-1) is a persistent and recurring disease that affects cattle
worldwide. It is a major contributor to bovine respiratory disease and reproductive failure in …
worldwide. It is a major contributor to bovine respiratory disease and reproductive failure in …