Acute inflammation or resolved inflammation is an adaptive host defense mechanism and is
self-limiting, which returns the body to a state of homeostasis. However, unresolved …

The endoplasmic reticulum (ER) is a multifunctional organelle required for lipid biosynthesis,
calcium storage, and protein folding and processing. A number of physiological and …

Chemoprevention has been considered as a possible approach for cancer prevention. A
significant effort has been made in the development of novel drugs for both cancer …

Alzheimer's disease (AD) is the most common form of dementia. It is characterized by
extracellular deposition of a specific protein, beta-amyloid peptide fibrils, and is …

Historically, anti-inflammatory drugs had their origins in the serendipitous discovery of
certain plants and their extracts being applied for the relief of pain, fever and inflammation …

Evidence from a wide range of sources suggests that individuals taking aspirin and related
non-steroidal anti-inflammatory drugs have reduced risk of large bowel cancer. Work in …

Objective: To investigate the effects of ibuprofen on cardiac fibrosis in a rat model of type 1
diabetes. Methods: The diabetic model was established by injecting streptozotocin into the …

The endoplasmic reticulum (ER) stress response constitutes a cellular process that can be
triggered by a great variety of conditions that cause imbalances in intracellular homeostasis …

Nonsteroidal anti‐inflammatory drugs (NSAIDs) comprise a heterogeneous group of
pharmacological agents used for the symptomatic treatment of fever, pain, and inflammation …

Once it became clear that inflammation takes place in the modulation of different
degenerative disease including neurodegenerative, cardiovascular, diabetes and cancer …