Pain is the primary motivation for seeking medical care. Although pain may subside as
inflammation resolves or an injury heals, it is increasingly evident that persistency of the pain …

The use of effective regimens for mitigating pain remain underutilized in research rodents
despite the general acceptance of both the ethical imperative and regulatory requirements …

ALS is characterized by progressive inability to execute movements. Motor neurons
innervating fast-twitch muscle-fibers preferentially degenerate. The reason for this …

Objective Osteoarthritis (OA) is a leading cause of chronic pain, yet OA pain management
remains poor. Age is the strongest predictor of OA development, and mechanisms driving …

Background Grip strength is a robust biomarker showing good reliability 1, 2 and prediction
of negative health outcomes. 3, 4 Low grip strength is associated with disability and …

Medicinal plants remain an invaluable source for therapeutics of diseases that affect
humanity. Sideritis bilgeriana (Lamiaceae) is medicinal plant used in Turkey folk medicine to …

Pain measures traditionally used in rodents record mere reflexes evoked by sensory stimuli;
the results thus may not fully reflect the human pain phenotype. Alterations in physical and …

Pain is a clinical syndrome arising from a variety of etiologies in a heterogeneous
population, which makes successfully treating the individual patient difficult. Organizations …

Background: Red marine algae have shown the potential to reduce inflammation, influence
microbiota, and provide neuroprotection. Objective: To examine the prebiotic properties of …

Arthritis is a widespread inflammatory disease associated with progressive articular surface
degradation, ongoing pain, and hyperalgesia causing the development of functional …