[HTML][HTML] Detection of viruses by inflammasomes
L Spel, F Martinon - Current opinion in virology, 2021 - Elsevier
The innate immune system has evolved mechanisms to keep the viral infection under control
and repair damaged tissues. Several pathways can identify the presence of pathogenic …
and repair damaged tissues. Several pathways can identify the presence of pathogenic …
Empagliflozin ameliorates vascular calcification in diabetic mice through inhibiting Bhlhe40-dependent NLRP3 inflammasome activation
X Li, Z Chen, X Sun, Y Yang, H Jin, N Liu - Acta Pharmacologica Sinica, 2024 - nature.com
Type 2 diabetes mellitus (T2DM) patients exhibit greater susceptibility to vascular
calcification (VC), which has a higher risk of death and disability. However, there is no …
calcification (VC), which has a higher risk of death and disability. However, there is no …
NLRP3 Inflammasome Pharmacological Inhibitors in Glycyrrhiza for NLRP3-Driven Diseases Treatment: Extinguishing the Fire of Inflammation
Z Wang, G Xu, Z Li, X Xiao, J Tang… - Journal of Inflammation …, 2022 - Taylor & Francis
Inflammation is the tissues' defense response after the body is stimulated by microbial
infection or damage signals, and it is initiated when pattern recognition receptors recognize …
infection or damage signals, and it is initiated when pattern recognition receptors recognize …
The interplay between tissue niche and macrophage cellular metabolism in obesity
S Daemen, JD Schilling - Frontiers in immunology, 2020 - frontiersin.org
Obesity is associated with the development of metabolic diseases such as type 2 diabetes
and non-alcoholic fatty liver disease. The presence of chronic, low-grade inflammation …
and non-alcoholic fatty liver disease. The presence of chronic, low-grade inflammation …
Tissue and circulating microRNAs as biomarkers of response to obesity treatment strategies
G Catanzaro, T Filardi, C Sabato, A Vacca… - Journal of …, 2021 - Springer
Background Obesity, characterized by an increased amount of adipose tissue, is a metabolic
chronic alteration which has reached pandemic proportion. Lifestyle changes are the first …
chronic alteration which has reached pandemic proportion. Lifestyle changes are the first …
Native low-density lipoproteins are priming signals of the NLRP3 inflammasome/interleukin-1β pathway in human adipose tissue and macrophages
S Bissonnette, V Lamantia, B Ouimet, Y Cyr… - Scientific Reports, 2023 - nature.com
Elevated plasma numbers of atherogenic apoB-lipoproteins (apoB), mostly as low-density
lipoproteins (LDL), predict diabetes risk by unclear mechanisms. Upregulation of the NLRP3 …
lipoproteins (LDL), predict diabetes risk by unclear mechanisms. Upregulation of the NLRP3 …
Reactive oxygen species-dependent-NLRP3 inflammasome activation in human neutrophils induced by l-amino acid oxidase derived from Calloselasma rhodostoma …
MV Paloschi, CN Boeno, JA Lopes, CMA Rego… - Life Sciences, 2022 - Elsevier
Abstract l-Amino acid oxidase isolated from Calloselasma rhodostoma (Cr-LAAO) snake
venom is a potent stimulus for neutrophil activation and production of inflammatory …
venom is a potent stimulus for neutrophil activation and production of inflammatory …
Pattern Recognition Receptor‐Mediated Chronic Inflammation in the Development and Progression of Obesity‐Related Metabolic Diseases
L Yu, Y Li, C Du, W Zhao, H Zhang… - Mediators of …, 2019 - Wiley Online Library
Obesity‐induced chronic inflammation is known to promote the development of many
metabolic diseases, especially insulin resistance, type 2 diabetes mellitus, nonalcoholic fatty …
metabolic diseases, especially insulin resistance, type 2 diabetes mellitus, nonalcoholic fatty …
SARS-CoV-2 viroporin triggers the NLRP3 inflammatory pathway
Cytokine storm resulting from a heightened inflammatory response is a prominent feature of
severe COVID-19 disease. This inflammatory response results from assembly/activation of a …
severe COVID-19 disease. This inflammatory response results from assembly/activation of a …
Molybdenum and cadmium co-induce pyroptosis via inhibiting Nrf2-mediated antioxidant defense response in the brain of ducks
Z Hu, G Nie, J Luo, R Hu, G Li, G Hu… - Biological Trace Element …, 2023 - Springer
Excess molybdenum (Mo) and cadmium (Cd) are harmful to animals, but the neurotoxic
mechanism co-induced by Mo and Cd is unclear. To estimate the effects of Mo and Cd co …
mechanism co-induced by Mo and Cd is unclear. To estimate the effects of Mo and Cd co …