Nutrigenomics is the study of the gene-nutrient interaction and it indicates that some
nutrients, called bioactive compounds, can mold the genetic expression or change the …

Background Diabetes is one of the most common metabolic diseases and continues to be a
leading cause of death worldwide. The NLRP3 inflammasome has been shown to exert …

Podocyte injury critically contributes to the pathogenesis of obesity‐related glomerulopathy
(ORG). Recently, lipid accumulation and inflammatory responses have been found to be …

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder. A genetic component
in the pathogenesis is highly likely considering that~ 30% to 40% of patients with HS report …

Drug-induced toxicity, which impairs human organ function, is a serious problem during drug
development that hinders the clinical use of many marketed drugs, and the underlying …

Context The NRLP3 inflammasome is a multiprotein danger-sensing complex that serves as
a critical link between obesity-related adipose inflammation and insulin resistance and has …

Background Obesity is associated with more severe asthma, however, the mechanisms
responsible are poorly understood. Obesity is also associated with low-grade systemic …

Purpose In men, obesity may lead to poor semen parameters and reduced fertility. However,
the causative links between obesity and male infertility are not totally clear, particularly on a …

Obesity-related diseases (eg type 2 diabetes mellitus and cardiovascular disorders)
represent an increasing health problem worldwide. NLRP3 inflammasome activation may …

Introduction Clinical differentiation between bipolar disorder (BD) and major depressive
disorder (MDD) is difficult. Research has therefore focused on discriminatory biological …