Ocular drug delivery

R Gaudana, HK Ananthula, A Parenky, AK Mitra - The AAPS journal, 2010 - Springer
Ocular drug delivery has been a major challenge to pharmacologists and drug delivery
scientists due to its unique anatomy and physiology. Static barriers (different layers of …

[HTML][HTML] Formulation considerations for the management of dry eye disease

P Agarwal, JP Craig, ID Rupenthal - Pharmaceutics, 2021 - mdpi.com
Dry eye disease (DED) is one of the most common ocular surface disorders characterised by
a deficiency in quality and/or quantity of the tear fluid. Due to its multifactorial nature …

Nanotechnology in ocular drug delivery

SK Sahoo, F Dilnawaz, S Krishnakumar - Drug discovery today, 2008 - Elsevier
Despite numerous scientific efforts, efficient ocular drug delivery remains a challenge for
pharmaceutical scientists. Most ocular diseases are treated by topical drug application in the …

Current challenges in non-invasive insulin delivery systems: a comparative review

ES Khafagy, M Morishita, Y Onuki… - Advanced drug delivery …, 2007 - Elsevier
The quest to eliminate the needle from insulin delivery and to replace it with non-or less-
invasive alternative routes has driven rigorous pharmaceutical research to replace the …

Recent advances in ophthalmic preparations: Ocular barriers, dosage forms and routes of administration

FA Maulvi, KH Shetty, DT Desai, DO Shah… - International journal of …, 2021 - Elsevier
The human eye is a complex organ with unique anatomy and physiology that restricts the
delivery of drugs to target ocular tissues/sites. Recent advances in the field of pharmacy …

[HTML][HTML] Topical drug delivery to the posterior segment of the eye

M Loescher, C Seiz, J Hurst, S Schnichels - Pharmaceutics, 2022 - mdpi.com
Topical drug delivery to the posterior segment of the eye is a very complex challenge.
However, topical delivery is highly desired, to achieve an easy-to-use treatment option for …

Nanoemulsions for drug delivery through different routes

P Thiagarajan - Research in biotechnology, 2011 - agris.fao.org
Utilising nanoemulsions as vehicles for carrying active pharmaceutical ingredients is
emerging as a promising approach for the lattersâ â ‚¬ â „¢ targeted delivery. For drug …

[HTML][HTML] Noninvasive routes of proteins and peptides drug delivery

PK Sharma, S Bansal, A Banik - Indian journal of pharmaceutical …, 2011 - ncbi.nlm.nih.gov
Recent advances in the field of pharmaceutical biotechnology have led to the formulation of
many protein and peptide-based drugs for therapeutic and clinical application. The route of …

Brinzolamide nanocrystal formulations for ophthalmic delivery: reduction of elevated intraocular pressure in vivo

A Tuomela, P Liu, J Puranen, S Rönkkö… - International journal of …, 2014 - Elsevier
Nanocrystal-based drug delivery systems provide important tools for ocular formulation
development, especially when considering poorly soluble drugs. The objective of the study …

Carboxymethyl tamarind kernel polysaccharide nanoparticles for ophthalmic drug delivery

H Kaur, M Ahuja, S Kumar, N Dilbaghi - International Journal of Biological …, 2012 - Elsevier
Tropicamide-loaded carboxymethyl tamarind kernel polysaccharide (CMTKP) nanoparticles
were prepared and evaluated for ocular delivery. Preparation of ionotropically gelled …