Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

The bioactive peptides galanin, spexin and kisspeptin have a common ancestral origin and
their pathophysiological roles are increasingly the subject of investigation. Evidence …

Neuropeptides released by hypothalamic neurons play a major role in the regulation of
feeding, acting both within the hypothalamus, and at other appetite regulating centres …

As one of the evolutionary oldest parts of the brain, the diencephalon evolved to harmonize
changing environmental conditions with the internal state for survival of the individual and …

Energy balance is maintained via a homeostatic system involving both the brain and the
periphery. A key component of this system is the hypothalamus. Over the past two decades …

The high prevalence of obesity and associated metabolic disorders are one of the major
public health problems worldwide. Among the main causal factors of obesity, excessive …

Preimplantation development directs the formation of an implantation-or attachment-
competent embryo so that metabolic interactions with the uterus can occur, pregnancy can …

Food reward, not hunger, is the main driving force behind eating in the modern obesogenic
environment. Palatable foods, generally calorie-dense and rich in sugar/fat, are thus readily …

The gonadotrophin‐releasing hormone (GnRH) secreting neurones, which form the final
common pathway for the central regulation of reproduction, are directly targeted by …

Objective: To characterize and compare three obesity-prone inbred strains, AKR/J, DBA/2J
and C57BL/6J, to three control strains, C3H/HeJ, BALB/cByJ and C57L/J, selected based on …