Osteoporosis (OP) constitutes a significant health concern that profoundly affects individuals'
quality of life. Bisphosphonates, conventional pharmaceuticals widely employed in OP …

Alendronate (ALN) is the most commonly prescribed oral nitrogen-containing
bisphosphonate for osteoporosis therapy. However, its administration is associated with …

Injectable hydrogel-based materials have emerged as promising alendronate (ALN) delivery
systems for the treatment of osteoporosis. However, their intrinsic permeability limits the …

Purpose Surgical site infections pose a significant challenge for medical services. Systemic
antibiotics may be insufficient in preventing bacterial biofilm development. With the local …

Surface modification, encompassing both chemical and physical features, plays a crucial
role in fulfilling the requirements of biomaterial applications and also improves their …

Electrospun composite nanofiber scaffolds are well known for their bone and tissue
regeneration applications. This research is focused on the development of PVP and PVA …

Currently, the relationship between serum uric acid (SUA) and bone mineral density (BMD)
in men remains controversial. This study aims to investigate the relationship between SUA …

Multiple myeloma (MM) is the second most prevalent hematological malignancy. Current
MM treatment strategies are hampered by systemic toxicity and suboptimal therapeutic …

Osteoporotic bone defects cannot withstand surgery with more significant trauma due to
bone fragility, while systemic drug therapy has formidable adverse effects. Consequently …

Alendronate and estradiol are potential molecules for the treatment of osteoporosis but their
use is limited by lower skin permeation and first-pass metabolism respectively. To develop a …