Recurrent meningitis

J Rosenberg, BT Galen - Current Pain and Headache Reports, 2017 - Springer
Abstract Purpose of Review Recurrent meningitis is a rare clinical scenario that can be self-
limiting or life threatening depending on the underlying etiology. This review describes the …

A phase I/II study of intrathecal trastuzumab in human epidermal growth factor receptor 2-positive (HER2-positive) cancer with leptomeningeal metastases: Safety …

PU Kumthekar, MJ Avram, AB Lassman, NU Lin… - Neuro …, 2023 - academic.oup.com
Background Patients with human epidermal growth factor receptor 2-positive (HER2-
positive) cancers have a high incidence of central nervous system (CNS) spread, but …

Optimal management of leptomeningeal carcinomatosis in breast cancer patients—a systematic review

S Dudani, S Mazzarello, J Hilton, B Hutton… - Clinical Breast …, 2016 - Elsevier
The incidence of leptomeningeal carcinomatosis in breast cancer patients (LC-BC) is
increasing. Despite significantly affecting patient quality of life (QoL) and overall survival …

Outcome and prognostic factors following palliative craniospinal irradiation for leptomeningeal carcinomatosis

RA El Shafie, K Böhm, D Weber, K Lang… - Cancer management …, 2019 - Taylor & Francis
Background Leptomeningeal carcinomatosis (LC) is a severe complication of metastatic
tumor spread to the central nervous system. Prognosis is dismal with a median overall …

Palliative radiotherapy for leptomeningeal carcinomatosis–analysis of outcome, prognostic factors, and symptom response

RA El Shafie, K Böhm, D Weber, K Lang… - Frontiers in …, 2019 - frontiersin.org
Introduction: The purpose of this article is to report our institution's 10-year experience on
palliative radiotherapy for the treatment of leptomeningeal carcinomatosis (LC), assessing …

Complications of intrathecal chemotherapy in adults: single‐institution experience in 109 consecutive patients

DM Byrnes, F Vargas, C Dermarkarian… - Journal of …, 2019 - Wiley Online Library
Acute lymphoblastic leukemia and other aggressive lymphoid malignancies like Burkitt
leukemia/lymphoma have high incidence of central nervous system (CNS) involvement …

Oncolytic HSV1 targets different growth phases of breast cancer leptomeningeal metastases

D Kuruppu, D Bhere, CT Farrar, K Shah… - Cancer Gene …, 2023 - nature.com
Leptomeningeal metastasis is a fatal complication of breast cancer which results when
cancer cells seed in the meninges. Currently there is no cure, limiting survival to less than …

Application of 3D fast spin-echo T1 black-blood imaging in the diagnosis and prognostic prediction of patients with leptomeningeal carcinomatosis

J Oh, SH Choi, E Lee, DJ Shin, SW Jo… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Contrast-enhanced 3D fast spin-echo T1 black-blood
imaging selectively suppresses the signal of blood flow and could provide a higher contrast …

A systematic review of craniospinal irradiation for leptomeningeal disease: past, present, and future

L Maillie, LR Salgado, S Lazarev - Clinical and Translational Oncology, 2021 - Springer
Purpose Leptomeningeal disease (LMD) is a rare but deadly complication of cancer in
which the disease spreads to the cerebrospinal fluid and seeds the meninges of the central …

A Comprehensive Review of Current Treatment Modalities for Leptomeningeal Carcinomatosis in Breast Cancer

CD Morris, C Humphrey, P Dillon - Critical Reviews in Oncology …, 2024 - Elsevier
Leptomeningeal carcinomatosis (LC) is a metastatic complication of breast cancer that
imparts a very poor prognosis and distressing neurologic symptoms in affected patients …