Wound healing occurs as a response to disruption of the epidermis and dermis. It is an
intricate and well-orchestrated response with the goal to restore skin integrity and function …

Background: In 2010, this Journal published my comprehensive review of the literature on
hypertrophic scars and keloids. In that article, I presented evidence-based algorithms for the …

Excessive connective tissue accumulation, a hallmark of hypertrophic scaring, results in
progressive deterioration of the structure and function of organs. It can also be seen during …

Keloid, a common dermal fibroproliferative disorder, is benign skin tumors characterized by
the aggressive fibroblasts proliferation and excessive accumulation of extracellular matrix …

Keloids are an excessive tissue response to dermal damage, characterized by uncontrolled
growth and a high recurrence rate after various treatments. Abnormalities with the …

Keloid and hypertrophic scar formation after orthopaedic surgical closure is a complex issue.
The nature and location of procedures maximize wound tension, leave foreign bodies, and …

One of the most significant adverse postburn responses is abnormal scar formation, such as
keloids. Despite its prolificacy, the underlying pathophysiology of keloid development is …

Significance: Hypertrophic scarring is a challenging issue for patients and clinicians. The
prevalence of hypertrophic scarring can be up to 70% after burns, and patients suffer from …

Background The pathophysiology of keloid formation is not yet understood, so the
identification of biomarkers for kelod can be one step towards designing new targeting …

Keloid, characterized by fibroproliferative disorders of the skin, can be developed in people
of different genders, ages and ethnicities. Keloid can appear in any part of the body but are …