Background Interstitial lung disease (ILD) is a common manifestation of idiopathic
inflammatory myopathies (IIM) and a substantial contributor to hospitalisation, increased …

Background Respiratory diseases are one of the leading causes of death worldwide, yet
effective treatment options remain limited. Although inflammation is thought to be a key …

Positron emission tomography (PET) is a quantitative molecular imaging modality
increasingly used to study pulmonary disease processes and drug effects on those …

The lungs are supplied by both the pulmonary arteries carrying deoxygenated blood
originating from the right ventricle and the bronchial arteries carrying oxygenated blood …

Purpose Pulmonary arterial hypertension (PAH) is a recognized complication of systemic
lupus erythematosus (SLE-PAH) patients and its lung pathology shares similarity to …

PET/CT quantification of lung tissue is limited by several difficulties: the lung density and
local volume changes during respiration, the anatomical mismatch between PET and CT …

Purpose: Tuberous sclerosis complex (TSC) is an autosomal dominant disorder caused by
inactivating mutations of the TSC1 or TSC2 gene, characterized by neurocognitive …

Purpose Imaging of acute lung inflammation is pivotal to evaluate innovative ventilation
strategies. We aimed to develop and validate a three-tissue compartment kinetic model …

Acute respiratory distress syndrome (ARDS) is a major cause of mortality in critically ill
patients. Patients are currently managed by protective ventilation and alveolar recruitment …

Early diagnosis of radiation-induced pulmonary fibrosis (RIPF) in lung cancer patients after
radiation therapy is important. A gastrin-releasing peptide receptor (GRPR) mediates the …