Tryptophan in health and disease

S Comai, A Bertazzo, M Brughera, S Crotti - Advances in clinical chemistry, 2020 - Elsevier
Tryptophan (TRP), an essential amino acid in mammals, is involved in several physiological
processes including neuronal function, immunity, and gut homeostasis. In humans, TRP is …

Effect of immune activation on the kynurenine pathway and depression symptoms–a systematic review and meta-analysis

C Hunt, TM e Cordeiro, R Suchting, C de Dios… - Neuroscience & …, 2020 - Elsevier
Dysregulated kynurenine (KYN) pathway has been implicated in the pathophysiology of
depression. In this systematic review, we examined the relationship between kynurenine …

[HTML][HTML] Serum Metabolic Profiles of the Tryptophan-Kynurenine Pathway in the high risk subjects of major depressive disorder

M Sakurai, Y Yamamoto, N Kanayama, M Hasegawa… - Scientific reports, 2020 - nature.com
Previous reports have shown that during chronic inflammation, the tryptophan (TRP)-
kynurenine (KYN) pathway plays a pivotal role in the onset of depression. The aim of this …

The role of anthranilic acid in the increase of depressive symptoms and major depressive disorder during treatment for hepatitis C with pegylated interferon-α2a and …

T Pawlowski, D Pawlak, M Inglot, M Zalewska… - Journal of Psychiatry and …, 2021 - jpn.ca
Background Tryptophan metabolism via the kynurenine pathway is considered the link
between the immune and endocrine systems. Dysregulation of serotonergic transmission …

[HTML][HTML] HTR1A, TPH2, and 5-HTTLPR polymorphisms and their impact on the severity of depressive symptoms and on the concentration of tryptophan catabolites …

T Pawlowski, K Malyszczak, D Pawlak, M Inglot… - Cells, 2023 - mdpi.com
Background: Seeing that there are no data about associations between serotonin gene
polymorphism and tryptophan catabolite concentration during PEG-IFN-α2a treatment, the …

The severity of depressive symptoms as an independent predictor of Sustained Virological Response during treatment for hepatitis C with pegylated interferon-α2a …

T Pawłowski, M Radkowski, K Perlejewski… - Psychosomatic …, 2023 - journals.lww.com
Objective Sustained virologic response (SVR) is the best indicator of successful therapy for
hepatitis C virus (HCV) infection. Patients with chronic HCV infection treated with pegylated …

Optimizing human performance in extreme environments through precision medicine: From spaceflight to high-performance operations on Earth

MA Schmidt, JA Jones, CE Mason - Cambridge Prisms: Precision …, 2023 - cambridge.org
Humans operating in extreme environments often conduct their operations at the edges of
the limits of human performance. Sometimes, they are required to push these limits to …

The year of immunopsychiatry: a special issue that foresaw the future

CM Pariante - Psychoneuroendocrinology, 2019 - pubmed.ncbi.nlm.nih.gov
The year of immunopsychiatry: A special issue that foresaw the future The year of
immunopsychiatry: A special issue that foresaw the future Psychoneuroendocrinology. 2019 …

[HTML][HTML] Integrated analyses of transcriptomics and network pharmacology reveal leukocyte characteristics and functional changes in subthreshold depression …

K Li, L You, J Zhen, G Huang, T Wang, Y Cai… - Journal of Traditional …, 2024 - Elsevier
Objective To investigate the molecular mechanism and identify potential drugs for
subthreshold depression (SD), and elucidate the detalied mechanism of Danzhi Xiaoyao …

Erkrankungen von Leber und Pankreas

HP Kapfhammer - Depression, Angst, traumatischer Stress und …, 2023 - Springer
In einer Perspektive der psychischen und somatischen Komorbidität werden folgende
Krankheiten der Leber und der Bauchspeicheldrüse betrachtet: Virus-Hepatitis C …