Myocardin-Related Transcription Factor Mediates Epithelial Fibrogenesis in Polycystic Kidney Disease
Z Lichner, M Ding, T Khare, Q Dan, R Benitez… - Cells, 2024 - mdpi.com
Polycystic kidney disease (PKD) is characterized by extensive cyst formation and
progressive fibrosis. However, the molecular mechanisms whereby the loss/loss-of-function …
progressive fibrosis. However, the molecular mechanisms whereby the loss/loss-of-function …
[HTML][HTML] Ciliogenesis defects after neurulation impact brain development and neuronal activity in larval zebrafish
Cilia are slender, hair-like structures extending from cell surfaces and playing essential roles
in diverse physiological processes. Within the nervous system, primary cilia contribute to …
in diverse physiological processes. Within the nervous system, primary cilia contribute to …
Cilia-mediated cerebrospinal fluid flow modulates neuronal and astroglial activity in the zebrafish larval brain.
The brain uses a specialized system to transport cerebrospinal fluid (CSF). This system
consists of interconnected ventricles lined by ependymal cells, which generate a directional …
consists of interconnected ventricles lined by ependymal cells, which generate a directional …
Loss of Bbs8 leads to cystic kidney disease in mice and affects tubulin acetylation through HDAC2
E Kieckhoefer, PA Matthiessen, LK Ebert, C Klausen… - bioRxiv, 2024 - biorxiv.org
Bardet-Biedl Syndrome (BBS) is a genetic disorder marked by considerable genetic and
phenotypic diversity. BBS often presents as a combination of retinitis pigmentosa, obesity …
phenotypic diversity. BBS often presents as a combination of retinitis pigmentosa, obesity …
The neuronal cilium–a highly diverse and dynamic organelle involved in sensory detection and neuromodulation
N Jurisch-Yaksi, D Wachten, J Gopalakrishnan - Trends in Neurosciences, 2024 - cell.com
Cilia are fascinating organelles that act as cellular antennae, sensing the cellular
environment. Cilia gained significant attention in the late 1990s after their dysfunction was …
environment. Cilia gained significant attention in the late 1990s after their dysfunction was …