Metformin and the risk of head and neck cancer: a case–control analysis

C Becker, SS Jick, CR Meier… - Diabetes, Obesity and …, 2014 - Wiley Online Library
Aims Metformin use has been associated with a decreased risk of some cancers, although
data on head and neck cancer (HNC) are scarce. We explored the relation between the use …

[HTML][HTML] The predictive power of CD3+ T cell infiltration of oral squamous cell tumors is limited to non-diabetic patients

G Spanier, I Ugele, F Nieberle, L Symeou… - Cancer Letters, 2021 - Elsevier
Diabetes mellitus type II (DM) and immune cell infiltration determine patient outcome in
many tumor entities. Here we studied a possible link between the metabolic and immune …

3q26‐29 Amplification in head and neck squamous cell carcinoma: a review of established and prospective oncogenes

MA Davidson, EJ Shanks - The FEBS Journal, 2017 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC) is significantly underrepresented in
worldwide cancer research, yet survival rates for the disease have remained static for over …

Metformin prevents the progression of dysplastic mucosa of the head and neck to carcinoma in nondiabetic patients

MZ Lerner, N Mor, H Paek, A Blitzer… - Annals of Otology …, 2017 - journals.sagepub.com
Objective: Metformin is an oral anti-hyperglycemic agent used to treat type 2 diabetes
mellitus (DM). In vitro and animal models have shown that metformin can prevent the …

Type 2 diabetes mellitus and risk of head and neck cancer subtypes: a systematic review and meta-analysis of observational studies

P Yan, Y Wang, X Yu, Y Liu, ZJ Zhang - Acta Diabetologica, 2021 - Springer
Aims The association between type 2 diabetes mellitus (T2DM) and risk of head and neck
cancer (HNC) remains unclear. This study aims to perform a system review and meta …

[HTML][HTML] Metabolic syndrome and risk of upper tract urothelial carcinoma: a case-control study from surveillance, epidemiology and end results-medicare-linked …

Y Lu, W Zhang, S Fan, Z Liang, Z Li, J Tian… - Frontiers in …, 2021 - frontiersin.org
Background Metabolic syndrome (MetS) and its components are associated with increased
risks of several cancers. However, the relationship between MetS and upper tract urothelial …

[HTML][HTML] Association between Metabolic Syndrome and Risk of Hypopharyngeal Cancer: A Nationwide Cohort Study from Korea

JW Kang, HK Cheong, SI Kim, MK Lee, YC Lee, IH Oh… - Cancers, 2023 - mdpi.com
Simple Summary The incidence of hypopharyngeal cancer has been rapidly increasing, but
hypopharyngeal cancer has a poorer prognosis compared to other head and neck cancers …

Risk factors of head and neck cancer mortality compared with those of all-cause and all-cancer mortalities

HM Cho, DW Lee, JJ Park, HM Choi… - Journal of Oral …, 2020 - jstage.jst.go.jp
This study aimed to clarify the risk factors of head and neck cancer (HNC) mortality, relative
to those of all-cause and all-cancer mortalities, using the Korean National Health Insurance …

Metabolic disorders and the risk of nasopharyngeal carcinoma: a case–control study in Italy

A Zucchetto, M Taborelli, C Bosetti… - European Journal of …, 2018 - journals.lww.com
The aim of this study is to evaluate the association between metabolic disorders and the risk
of nasopharyngeal carcinoma, considering different histological subtypes. Between 1992 …

Metabolic disorders and the risk of head and neck cancer: a protocol for a systematic review and meta-analysis

A Gormley, C Richards, F Spiga, E Gray, J Hooper… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Head and neck cancer squamous cell carcinoma (HNSCC) is the sixth most
common cancer internationally. Established risk factors include smoking, alcohol and …