[HTML][HTML] Signaling pathways and therapeutic interventions in gastric cancer
Gastric cancer (GC) ranks fifth in global cancer diagnosis and fourth in cancer-related death.
Despite tremendous progress in diagnosis and therapeutic strategies and significant …
Despite tremendous progress in diagnosis and therapeutic strategies and significant …
Lactic acid in macrophage polarization: The significant role in inflammation and cancer
H Zhou, XY Yan, W Yu, X Liang, X Du… - International reviews …, 2022 - Taylor & Francis
Metabolite lactic acid has always been regarded as a metabolic by-product rather than a
bioactive molecule. Recently, this view has changed since it was discovered that lactic acid …
bioactive molecule. Recently, this view has changed since it was discovered that lactic acid …
[HTML][HTML] Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients
Results The entire database incorporates 1,065 gastric carcinoma samples, gene
expression data. Out of 29 established markers, higher expression of BECN1 (HR= 0.68, p …
expression data. Out of 29 established markers, higher expression of BECN1 (HR= 0.68, p …
Nanoparticle-based drug delivery systems to overcome gastric cancer drug resistance
Gastric cancer (GC) results from deregulated cell growth in the stomach. Despite significant
efforts and recent advancements in the treatment of gastric cancer, it remains a life …
efforts and recent advancements in the treatment of gastric cancer, it remains a life …
[HTML][HTML] Inflammation-related factors predicting prognosis of gastric cancer
WJ Chang, Y Du, X Zhao, LY Ma… - World journal of …, 2014 - ncbi.nlm.nih.gov
Gastric cancer (GC), which is mainly induced by Helicobacter pylori (H. pylori) infection, is
one of the leading causes of cancer-related death in the developing world. Active …
one of the leading causes of cancer-related death in the developing world. Active …
[HTML][HTML] Knockdown of m6A reader IGF2BP3 inhibited hypoxia-induced cell migration and angiogenesis by regulating hypoxia inducible factor-1α in stomach cancer
L Jiang, Y Li, Y He, D Wei, L Yan, H Wen - Frontiers in Oncology, 2021 - frontiersin.org
Hypoxia is a common feature of solid tumors including stomach cancer (SC) and is closely
associated with cancer malignant progression. N6-methyladenosine (m6A), a common …
associated with cancer malignant progression. N6-methyladenosine (m6A), a common …
Metabolic reprogramming results in abnormal glycolysis in gastric cancer: a review
Y Liu, Z Zhang, J Wang, C Chen, X Tang… - OncoTargets and …, 2019 - Taylor & Francis
The Warburg effect in tumor cells involves the uptake of high levels of glucose, enhanced
glycolysis, and the metabolism of pyruvate to lactic acid rather than oxidative phos …
glycolysis, and the metabolism of pyruvate to lactic acid rather than oxidative phos …
A review of research progress in multidrug-resistance mechanisms in gastric cancer
T Ruan, W Liu, K Tao, C Wu - OncoTargets and therapy, 2020 - Taylor & Francis
Gastric cancer is one of the most common malignant tumors, and it is also one of the leading
causes of cancer death worldwide. Because of its insidious symptoms and lack of early …
causes of cancer death worldwide. Because of its insidious symptoms and lack of early …
[HTML][HTML] Gastric cancer: molecular mechanisms, novel targets, and immunotherapies: from bench to clinical therapeutics
T Baccili Cury Megid, AR Farooq, X Wang, E Elimova - Cancers, 2023 - mdpi.com
Simple Summary Gastric cancer (GC) is common but often diagnosed late. Recent advances
in chemotherapy, targeted therapy, and immunotherapy offer promising treatments …
in chemotherapy, targeted therapy, and immunotherapy offer promising treatments …
[HTML][HTML] Clinical and prognostic significance of HIF-1α overexpression in oral squamous cell carcinoma: a meta-analysis
J Zhou, S Huang, L Wang, X Yuan, Q Dong… - World Journal of …, 2017 - Springer
Background Recent studies have indicated an association between hypoxia inducible factor-
1 alpha (HIF-1α) expression and poor prognosis in patients with oral squamous cell …
1 alpha (HIF-1α) expression and poor prognosis in patients with oral squamous cell …