Obesity is a chronic and complex medical condition associated with a large number of
complications affecting most organs and systems through multiple pathways. Strategies for …

Long-term mechanical ventilation is a well-established treatment for chronic hypercapnic
respiratory failure (CHRF). It is aimed at improving CHRF-related symptoms, health-related …

Recent literature has raised concerns regarding the risk of adverse psychiatric events
among bariatric surgery patients. However, the relationship between weight loss therapy …

Background: Bariatric surgery is currently the most efficacious treatment for obesity and its
associated metabolic co-morbidities, such as diabetes. The metabolic improvements occur …

Rationale: Leptin treats upper airway obstruction and alveolar hypoventilation in leptin-
deficient ob/ob mice. However, obese humans and mice with diet-induced obesity (DIO) are …

Background: Obstructive sleep apnoea (OSA) and obesity are two common conditions
affecting the Australian population; obesity is the major risk factor for OSA. Objectives: The …

Diet, exercise, cognitive behavioral therapy and pharmacotherapy are some of the means of
assisting patients to lose weight, with bariatric surgery being the most effective. Over the last …

Importance Few large-scale long-term prospective cohort studies have assessed changes in
antidiabetes treatment after bariatric surgery. Objective To describe the association between …

Abstract Background The National Bariatric Surgery Registry (NBSR) is the largest bespoke
database in the field in the United Kingdom. Objectives Our aim was to analyze the NBSR to …

Rationale: Obesity hypoventilation syndrome (OHS) is an undesirable consequence of
obesity. Weight loss is an important component of management based on clinical rationale …