[HTML][HTML] Microbial production of polyunsaturated fatty acids—high-value ingredients for aquafeed, superfoods, and pharmaceuticals
S Jovanovic, D Dietrich, J Becker, M Kohlstedt… - Current opinion in …, 2021 - Elsevier
Highlights•PUFAs are applied worldwide in superfoods, aquafeed and pharmaceuticals.•
Climate warming and declining fishery cause a severe supply and demand gap.•The PUFAs …
Climate warming and declining fishery cause a severe supply and demand gap.•The PUFAs …
Advances in developing metabolically engineered microbial platforms to produce fourth-generation biofuels and high-value biochemicals
Producing bio-based chemicals is imperative to establish an eco-friendly circular
bioeconomy. However, the compromised titer of these biochemicals hampers their …
bioeconomy. However, the compromised titer of these biochemicals hampers their …
Synthetic metabolic pathways for conversion of CO2 into secreted short-to medium-chain hydrocarbons using cyanobacteria
The objective of this study was to implement direct sunlight-driven conversion of CO 2 into a
naturally excreted ready-to-use fuel. We engineered four different synthetic metabolic …
naturally excreted ready-to-use fuel. We engineered four different synthetic metabolic …
Engineering salt tolerance of photosynthetic cyanobacteria for seawater utilization
Photosynthetic cyanobacteria are capable of utilizing sunlight and CO 2 as sole energy and
carbon sources, respectively. With genetically modified cyanobacteria being used as a …
carbon sources, respectively. With genetically modified cyanobacteria being used as a …
Engineering the fatty acid synthesis pathway in Synechococcus elongatus PCC 7942 improves omega-3 fatty acid production
M Santos-Merino, MP Garcillán-Barcia… - Biotechnology for …, 2018 - Springer
Background The microbial production of fatty acids has received great attention in the last
few years as feedstock for the production of renewable energy. The main advantage of using …
few years as feedstock for the production of renewable energy. The main advantage of using …
Cellular engineering strategies toward sustainable omega-3 long chain polyunsaturated fatty acids production: State of the art and perspectives
Long-chain polyunsaturated fatty acids (LC-PUFAs) especially ω-3 fatty acids provide
significant health benefits for human beings. However, ω-3 LC-PUFAs cannot be …
significant health benefits for human beings. However, ω-3 LC-PUFAs cannot be …
Highlighting the potential of Synechococcus elongatus PCC 7942 as platform to produce α-linolenic acid through an updated genome-scale metabolic modeling
M Santos-Merino, Á Gargantilla-Becerra… - Frontiers in …, 2023 - frontiersin.org
Cyanobacteria are prokaryotic organisms that capture energy from sunlight using oxygenic
photosynthesis and transform CO2 into products of interest such as fatty acids …
photosynthesis and transform CO2 into products of interest such as fatty acids …
Synthetic biology in marine cyanobacteria: Advances and challenges
B Bourgade, K Stensjö - Frontiers in Microbiology, 2022 - frontiersin.org
The current economic and environmental context requests an accelerating development of
sustainable alternatives for the production of various target compounds. Biological …
sustainable alternatives for the production of various target compounds. Biological …
Synechococcus elongatus PCC 7942 as a Platform for Bioproduction of Omega-3 Fatty Acids
M Santos-Merino, R Gutiérrez-Lanza, J Nogales… - Life, 2022 - mdpi.com
Alpha-linolenic acid and stearidonic acid are precursors of omega-3 polyunsaturated fatty
acids, essential nutrients in the human diet. The ability of cyanobacteria to directly convert …
acids, essential nutrients in the human diet. The ability of cyanobacteria to directly convert …
Recent advances on essential fatty acid biosynthesis and production: clarifying the roles of Δ12/Δ15 fatty acid desaturase
C Wu, B Hong, S Jiang, X Luo, H Lin, Y Zhou… - Biochemical …, 2022 - Elsevier
Essential fatty acids (EFAs) provide various biological and physiological benefits; however,
they cannot be synthesised in the human body, and their intake must be derived from the …
they cannot be synthesised in the human body, and their intake must be derived from the …