Network pharmacology in research of Chinese medicine formula: methodology, application and prospective

T Luo, Y Lu, S Yan, X Xiao, X Rong, J Guo - Chinese journal of integrative …, 2020 - Springer
Chinese medicine (CM) is usually prescribed as CM formula to treat disease. The lack of
effective research approach makes it difficult to elucidate the molecular mechanisms of CM …

[HTML][HTML] Systems pharmacology for investigation of the mechanisms of action of traditional Chinese medicine in drug discovery

W Zhang, Y Huai, Z Miao, A Qian… - Frontiers in pharmacology, 2019 - frontiersin.org
As a traditional medical intervention in Asia and a complementary and alternative medicine
in western countries, traditional Chinese medicine (TCM) has attracted global attention in …

[HTML][HTML] BATMAN-TCM: a bioinformatics analysis tool for molecular mechANism of traditional Chinese medicine

Z Liu, F Guo, Y Wang, C Li, X Zhang, H Li, L Diao… - Scientific reports, 2016 - nature.com
Abstract Traditional Chinese Medicine (TCM), with a history of thousands of years of clinical
practice, is gaining more and more attention and application worldwide. And TCM-based …

[HTML][HTML] TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

J Ru, P Li, J Wang, W Zhou, B Li, C Huang, P Li… - Journal of …, 2014 - Springer
Background Modern medicine often clashes with traditional medicine such as Chinese
herbal medicine because of the little understanding of the underlying mechanisms of action …

Network medicine framework reveals generic herb-symptom effectiveness of traditional Chinese medicine

X Gan, Z Shu, X Wang, D Yan, J Li, S Ofaim… - Science …, 2023 - science.org
Understanding natural and traditional medicine can lead to world-changing drug
discoveries. Despite the therapeutic effectiveness of individual herbs, traditional Chinese …

Large-scale exploration and analysis of drug combinations

P Li, C Huang, Y Fu, J Wang, Z Wu, J Ru… - …, 2015 - academic.oup.com
Motivation: Drug combinations are a promising strategy for combating complex diseases by
improving the efficacy and reducing corresponding side effects. Currently, a widely studied …

Recent advances in natural small molecules as drug delivery systems

S Fu, X Yang - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Drug delivery systems (DDSs) are a multidisciplinary approach toward the effective delivery
of drugs to their target sites. Natural small molecule (NSM) compounds with anticancer …

[HTML][HTML] Licorice ameliorates cisplatin-induced hepatotoxicity through antiapoptosis, antioxidative stress, anti-inflammation, and acceleration of metabolism

Q Man, Y Deng, P Li, J Ma, Z Yang, X Yang… - Frontiers in …, 2020 - frontiersin.org
Cisplatin (CP) is one of the most effective antitumor drugs in the clinic, but has serious
adverse reactions, and its hepatotoxicity has not been fully investigated. Licorice (GC), a …

Can network pharmacology identify the anti-virus and anti-inflammatory activities of Shuanghuanglian oral liquid used in Chinese medicine for respiratory tract …

Z Zhuang, J Wen, L Zhang, M Zhang, X Zhong… - European Journal of …, 2020 - Elsevier
Introduction Shuanghuanglian (SHL) oral liquid is a well-known traditional Chinese
medicine preparation administered for respiratory tract infections in China. However, the …

[HTML][HTML] Systems pharmacology exploration of botanic drug pairs reveals the mechanism for treating different diseases

W Zhou, J Wang, Z Wu, C Huang, A Lu, Y Wang - Scientific reports, 2016 - nature.com
Multi-herb therapy has been widely used in Traditional Chinese medicine and tailored to
meet the specific needs of each individual. However, the potential molecular or systems …