Network pharmacology in research of Chinese medicine formula: methodology, application and prospective
T Luo, Y Lu, S Yan, X Xiao, X Rong, J Guo - Chinese journal of integrative …, 2020 - Springer
Chinese medicine (CM) is usually prescribed as CM formula to treat disease. The lack of
effective research approach makes it difficult to elucidate the molecular mechanisms of CM …
effective research approach makes it difficult to elucidate the molecular mechanisms of CM …
[HTML][HTML] Systems pharmacology for investigation of the mechanisms of action of traditional Chinese medicine in drug discovery
W Zhang, Y Huai, Z Miao, A Qian… - Frontiers in pharmacology, 2019 - frontiersin.org
As a traditional medical intervention in Asia and a complementary and alternative medicine
in western countries, traditional Chinese medicine (TCM) has attracted global attention in …
in western countries, traditional Chinese medicine (TCM) has attracted global attention in …
[HTML][HTML] BATMAN-TCM: a bioinformatics analysis tool for molecular mechANism of traditional Chinese medicine
Z Liu, F Guo, Y Wang, C Li, X Zhang, H Li, L Diao… - Scientific reports, 2016 - nature.com
Abstract Traditional Chinese Medicine (TCM), with a history of thousands of years of clinical
practice, is gaining more and more attention and application worldwide. And TCM-based …
practice, is gaining more and more attention and application worldwide. And TCM-based …
[HTML][HTML] TCMSP: a database of systems pharmacology for drug discovery from herbal medicines
Background Modern medicine often clashes with traditional medicine such as Chinese
herbal medicine because of the little understanding of the underlying mechanisms of action …
herbal medicine because of the little understanding of the underlying mechanisms of action …
Network medicine framework reveals generic herb-symptom effectiveness of traditional Chinese medicine
Understanding natural and traditional medicine can lead to world-changing drug
discoveries. Despite the therapeutic effectiveness of individual herbs, traditional Chinese …
discoveries. Despite the therapeutic effectiveness of individual herbs, traditional Chinese …
Large-scale exploration and analysis of drug combinations
Motivation: Drug combinations are a promising strategy for combating complex diseases by
improving the efficacy and reducing corresponding side effects. Currently, a widely studied …
improving the efficacy and reducing corresponding side effects. Currently, a widely studied …
Recent advances in natural small molecules as drug delivery systems
S Fu, X Yang - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Drug delivery systems (DDSs) are a multidisciplinary approach toward the effective delivery
of drugs to their target sites. Natural small molecule (NSM) compounds with anticancer …
of drugs to their target sites. Natural small molecule (NSM) compounds with anticancer …
[HTML][HTML] Licorice ameliorates cisplatin-induced hepatotoxicity through antiapoptosis, antioxidative stress, anti-inflammation, and acceleration of metabolism
Q Man, Y Deng, P Li, J Ma, Z Yang, X Yang… - Frontiers in …, 2020 - frontiersin.org
Cisplatin (CP) is one of the most effective antitumor drugs in the clinic, but has serious
adverse reactions, and its hepatotoxicity has not been fully investigated. Licorice (GC), a …
adverse reactions, and its hepatotoxicity has not been fully investigated. Licorice (GC), a …
Can network pharmacology identify the anti-virus and anti-inflammatory activities of Shuanghuanglian oral liquid used in Chinese medicine for respiratory tract …
Z Zhuang, J Wen, L Zhang, M Zhang, X Zhong… - European Journal of …, 2020 - Elsevier
Introduction Shuanghuanglian (SHL) oral liquid is a well-known traditional Chinese
medicine preparation administered for respiratory tract infections in China. However, the …
medicine preparation administered for respiratory tract infections in China. However, the …
[HTML][HTML] Systems pharmacology exploration of botanic drug pairs reveals the mechanism for treating different diseases
Multi-herb therapy has been widely used in Traditional Chinese medicine and tailored to
meet the specific needs of each individual. However, the potential molecular or systems …
meet the specific needs of each individual. However, the potential molecular or systems …