Exosomes: Large-scale production, isolation, drug loading efficiency, and biodistribution and uptake

I Kimiz-Gebologlu, SS Oncel - Journal of Controlled Release, 2022 - Elsevier
Exosomes are nanovesicles with different contents that play a role in various biological and
pathological processes. It offers significant advantages over other delivery systems such as …

[HTML][HTML] Exosomal cargos-mediated metabolic reprogramming in tumor microenvironment

S Tan, Y Yang, W Yang, Y Han, L Huang… - Journal of Experimental …, 2023 - Springer
Metabolic reprogramming is one of the hallmarks of cancer. As nutrients are scarce in the
tumor microenvironment (TME), tumor cells adopt multiple metabolic adaptations to meet …

[HTML][HTML] Exosomal targeting and its potential clinical application

J He, W Ren, W Wang, W Han, L Jiang… - Drug Delivery and …, 2022 - Springer
Exosomes are extracellular vesicles secreted by a variety of living cells, which have a
certain degree of natural targeting as nano-carriers. Almost all exosomes released by cells …

[HTML][HTML] Extracellular vesicles as bioactive nanotherapeutics: an emerging paradigm for regenerative medicine

M Li, F Fang, M Sun, Y Zhang, M Hu, J Zhang - Theranostics, 2022 - ncbi.nlm.nih.gov
In recent decades, extracellular vesicles (EVs), as bioactive cell-secreted nanoparticles
which are involved in various physiological and pathological processes including cell …

Recent microfluidic advances in submicron to nanoparticle manipulation and separation

S Hettiarachchi, H Cha, L Ouyang, A Mudugamuwa… - Lab on a Chip, 2023 - pubs.rsc.org
Manipulation and separation of submicron and nanoparticles are indispensable in many
chemical, biological, medical, and environmental applications. Conventional technologies …

[HTML][HTML] Extracellular vesicles: A rising star for therapeutics and drug delivery

S Du, Y Guan, A Xie, Z Yan, S Gao, W Li, L Rao… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …

Unraveling multilayered extracellular vesicles: Speculation on cause

K Broad, SA Walker, I Davidovich… - Journal of …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are cell‐released, heterogenous nanoparticles that play
important roles in (patho) physiological processes through intercellular communication. EVs …

Carbon‐based nanomaterials and sensing tools for wearable health monitoring devices

Ö Erdem, E Derin, S Zeibi Shirejini… - Advanced Materials …, 2022 - Wiley Online Library
The healthcare system has a drastic paradigm shift from centralized care to home‐based
and self‐monitoring strategies; aiming to reach more individuals, minimize workload in …

Engineering extracellular vesicles as delivery systems in therapeutic applications

L Wang, D Wang, Z Ye, J Xu - Advanced Science, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are transport vesicles secreted by living cells and released into
the extracellular environment. Recent studies have shown that EVs serve as “messengers” …

[HTML][HTML] Exosomes: a potential diagnostic and treatment modality in the quest for counteracting cancer

G Patel, TG Agnihotri, M Gitte, T Shinde, SS Gomte… - Cellular Oncology, 2023 - Springer
Background Exosomes are nanosized bio vesicles formed when multivesicular bodies and
the plasma membrane merge and discharge into bodily fluids. They are well recognized for …