The invention of hyperpolarized (HP) noble gas MRI using helium-3 (3 He) or xenon-129
(129 Xe) has provided a new method to evaluate lung function. Using HP 3 He or 129 Xe for …

The introduction of hyperpolarized gases (3He and 129Xe) has opened the door to
applications for which gaseous agents are uniquely suited—lung MRI. One of the pulmonary …

Clinical imaging has played an important role in the description of bronchopulmonary
dysplasia (BPD) or chronic lung disease of prematurity since its initial recognition. Northway …

Hyperpolarized xenon‐129 has the potential to become a noninvasive contrast agent for
lung MRI. In addition to its utility for imaging of ventilated airspaces, the property of xenon to …

Lung imaging using conventional 1H MRI presents great challenges because of the low
density of lung tissue, lung motion and very fast lung tissue transverse relaxation (typical T2 …

Hyperpolarized noble gases (HNGs), polarized to approximately 50% or higher, have led to
major advances in magnetic resonance (MR) imaging of porous structures and air-filled …

A close interaction between the respiratory pump, pulmonary parenchyma and blood
circulation is essential for a normal lung function. Many pulmonary diseases present …

Purpose To characterize the effect of diffusion time on short‐range hyperpolarized 3He
magnetic resonance imaging (MRI) diffusion measurements across a wide range of …

RATIONALE AND OBJECTIVES: The use of hyperpolarized 3He magnetic resonance
imaging as a quantitative lung imaging tool has progressed rapidly in the past decade …

The assessment of early pulmonary disease and its severity can be difficult in young
children, as procedures such as spirometry cannot be performed on them. Computed …