The tumor microenvironment is highly complex, and immune escape is currently considered
an important hallmark of cancer, largely contributing to tumor progression and metastasis …

Natural killer (NK) cells are innate immune cells that are critical to the body's antitumor and
antimetastatic defense. As such, novel therapies are being developed to utilize NK cells as …

Chronic inflammation is a known risk factor for gastrointestinal cancer. The evidence that
nonsteroidal anti-inflammatory drugs suppress the incidence, growth, and metastasis of …

Gene-engineered immune cell therapies have partially transformed cancer treatment, as
exemplified by the use of chimeric antigen receptor (CAR)-T cells in certain hematologic …

The clinical success of immunotherapy has revolutionized the treatment of cancer patients,
bringing renewed attention to tumor-infiltrating lymphocytes (TILs) of various cancer types …

Aim We aimed to develop and validate a comprehensive nomogram containing pre-
treatment plasma HSP90AA1 to predict the risk of breast cancer onset and metastasis …

Simple Summary Late-stage colorectal cancer treatment often involves chemotherapy and
radiation that can cause dose-limiting toxicity, and therefore there is great interest in …

Colorectal cancer (CRC) is a malignancy in the gastro-intestinal (GI) tract which has very
limited treatment options still, despite the vast amount of research undertaken. CRC was first …

Conventional αβ CAR-T cell-based approaches have revolutionized the field of cancer
immunotherapy, but hurdles remain, especially for solid tumors. Novel strategies in …

Simple Summary Natural Killer cells are known to eliminate tumors directly or via antibody
dependent cellular cytotoxicity. The complete modes and mechanisms of such killings are …