Screening of ToxCast chemicals responsible for human adverse outcomes with exposure to ambient air

L Qiao, L Gao, D Huang, Y Liu, C Xu, D Li… - … Science & Technology, 2022 - ACS Publications
Air pollution poses a major threat to global public health. Although there have been a few
investigations into the relationships between organic pollutants and adverse outcomes, the …

Accessing an expanded exposure science module at the comparative toxicogenomics database

CJ Grondin, AP Davis, TC Wiegers… - Environmental …, 2018 - ehp.niehs.nih.gov
The Comparative Toxicogenomics Database (CTD; http://ctdbase. org) is a free resource that
provides manually curated information on chemical, gene, phenotype, and disease …

A novel human biomonitoring study by semiconductor gas sensors in exposomics: investigation of health risk in contaminated sites

V Longo, A Forleo, AV Radogna, P Siciliano… - Environmental …, 2022 - Elsevier
Two areas in central-southern Italy Land of Fires in Campania and Valley of Sacco river in
Lazio are known to be contaminated sites, the first due to illegal fly-tipping and toxic fires …

[HTML][HTML] A strategy to validate a selection of human effect biomarkers using adverse outcome pathways: Proof of concept for phthalates and reproductive effects

KA Baken, N Lambrechts, S Remy, V Mustieles… - Environmental …, 2019 - Elsevier
Human biomonitoring measures the concentrations of environmental chemicals or their
metabolites in body fluids or tissues. Complementing exposure biomarkers with …

Strategies for drawing quantitative conclusions from nontargeted liquid chromatography–high-resolution mass spectrometry analysis

A Kruve - 2020 - ACS Publications
This Feature aims at giving an overview of different possibilities for quantitatively comparing
the results obtained from LC− HRMS-based nontargeted analysis. More specifically …

A call for a Human Exposome Project

T Hartung - ALTEX-Alternatives to animal experimentation, 2023 - altex.org
Four decades of the Human Genome Project and its consequences have shown how the
entrepreneurial state, through significant investment into science, can drive scientific …

Multicompartment and cross-species monitoring of contaminants of emerging concern in an estuarine habitat

TH Miller, KT Ng, A Lamphiere, TC Cameron… - Environmental …, 2021 - Elsevier
The fate of many chemicals in the environment, particularly contaminants of emerging
concern (CEC), have been characterised to a limited extent with a major focus on …

[HTML][HTML] Implementation of effect biomarkers in human biomonitoring studies: A systematic approach synergizing toxicological and epidemiological knowledge

A Rodríguez-Carrillo, V Mustieles… - International Journal of …, 2023 - Elsevier
Human biomonitoring (HBM) studies have highlighted widespread daily exposure to
environmental chemicals. Some of these are suspected to contribute to adverse health …

Mixed “antiandrogenic” chemicals at low individual doses produce reproductive tract malformations in the male rat

JM Conley, CS Lambright, N Evans… - Toxicological …, 2018 - academic.oup.com
Biomonitoring efforts have clearly shown that all humans are exposed to chemical mixtures.
Of concern is whether or not exposure to mixtures during pregnancy contributes to …

Vertical stratification in urban green space aerobiomes

JM Robinson, C Cando-Dumancela… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Exposure to a diverse environmental microbiome is thought to play an
important role in “educating” the immune system and facilitating competitive exclusion of …