The heart is the first functional organ to form during vertebrate development. Congenital
heart defects are the most common type of human birth defect, many originating as …

Abstract Congenital Heart Disease (CHD), malformations of the heart present at birth, is the
most common class of life-threatening birth defect (Hoffman (1995)[1], Gelb (2004)[2], Gelb …

Pacemaker cardiomyocytes that create the sinoatrial node are essential for the initiation and
maintenance of proper heart rhythm. However, illuminating developmental cues that direct …

The cardiac developmental network has been associated with myocardial regenerative
potential. However, the embryonic signals triggered following injury have yet to be fully …

Intra-organ communication guides morphogenetic processes that are essential for an organ
to carry out complex physiological functions. In the heart, the growth of the myocardium is …

Maintenance of cardiomyocyte identity is vital for normal heart development and function.
However, our understanding of cardiomyocyte plasticity remains incomplete. Here, we show …

Proper development and function of the vertebrate heart is vital for embryonic and postnatal
life. Many congenital heart defects in humans are associated with disruption of genes that …

Isoflucypram belongs to the new generation of succinate dehydrogenase inhibitor (SDHI)
fungicides that are commonly used in crop fungal disease control. Evidence indicates that …

Bixafen (BIX) is a succinate dehydrogenase inhibitor (SDHI)-class fungicide that is used to
control crop diseases. However, data on the toxicity of BIX to zebrafish are limited. Here …

The roles of long non-coding RNA (LncRNA) have been highlighted in various development
processes including congenital heart defects (CHD). Here, we characterized the molecular …