Riding the metal wave: A review of the latest developments in metal-based anticancer agents

S Abdolmaleki, A Aliabadi, S Khaksar - Coordination Chemistry Reviews, 2024 - Elsevier
Metal-based complexes have demonstrated significant anticancer effects and have emerged
as candidates with great potential for cancer therapy. These agents are effective in a variety …

[HTML][HTML] Recent Trends in the development of novel metal-based antineoplastic drugs

L Todorov, I Kostova - Molecules, 2023 - mdpi.com
Since the accidental discovery of the anticancer properties of cisplatin more than half a
century ago, significant efforts by the broad scientific community have been and are currently …

[HTML][HTML] A review on metal complexes and its anti-cancer activities: Recent updates from in vivo studies

S Adhikari, P Nath, A Das, A Datta, N Baildya… - Biomedicine & …, 2024 - Elsevier
Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …

[HTML][HTML] The importance of being Casiopeina as polypharmacologycal profile (mixed chelate–copper (II) complexes and their in vitro and in vivo activities)

Z Aguilar-Jiménez, A Espinoza-Guillén… - Inorganics, 2023 - mdpi.com
In this review, we present a timeline that shows the origin of mixed chelate copper (II)
complexes, registered as Mark Title Casiopeínas®, as the first copper (II) compounds …

[HTML][HTML] The lung microbiome in COPD and lung cancer: Exploring the potential of metal-based drugs

M O'Shaughnessy, O Sheils, AM Baird - International Journal of …, 2023 - mdpi.com
Chronic obstructive pulmonary disease (COPD) and lung cancer 17 are two of the most
prevalent and debilitating respiratory diseases worldwide, both associated with high …

Reaction Behavior of [1,3-Diethyl-4,5-diphenyl-1H-imidazol-2-ylidene] Containing Gold(I/III) Complexes against Ingredients of the Cell Culture Medium and the …

P Kapitza, A Scherfler, S Salcher… - Journal of Medicinal …, 2023 - ACS Publications
The reactivities of halido [1, 3-diethyl-4, 5-diphenyl-1 H-imidazol-2-ylidene] gold (I)(chlorido
(5), bromido (6), iodido (7)), bis [1, 3-diethyl-4, 5-diphenyl-1 H-imidazol-2-ylidene] gold (I)(8) …

[HTML][HTML] Antioxidant and anticancer potential of the new Cu (II) complexes bearing imine-phenolate ligands with pendant amine N-donor groups

AC Pinheiro, IJ Nunes, WV Ferreira, PP Tomasini… - Pharmaceutics, 2023 - mdpi.com
Cu (II) complexes bearing NNO-donor Schiff base ligands (2a, b) have been synthesized
and characterized. The single crystal X-ray analysis of the 2a complex revealed that a …

[HTML][HTML] Metal-based complexes in cancer

C Riccardi, M Piccolo - International Journal of Molecular Sciences, 2023 - mdpi.com
Indeed, metal-containing complexes are endowed with impressive chemical diversity and
versatility, depending on the metal of choice, its oxidation state, the number and type of …

[HTML][HTML] Research Progress of Metal Anticancer Drugs

Y Bai, G Aodeng, L Ga, W Hai, J Ai - Pharmaceutics, 2023 - mdpi.com
Cancer treatments, including traditional chemotherapy, have failed to cure human
malignancies. The main reasons for the failure of these treatments are the inevitable drug …

Oxo-centered trinuclear ruthenium acetates: Structure and applications

S Nikolaou, LGA do Nascimento… - Coordination Chemistry …, 2023 - Elsevier
Polynuclear μ-oxo complexes are commonly observed for second and third row transition
metals. This review is particularly interested in the μ 3-oxo-bridged ruthenium trinuclear …