The epigenetic modifications of histones are versatile marks that are intimately connected to
development and disease pathogenesis including human cancers. In this review, we will …

Histone posttranslational modifications represent a versatile set of epigenetic marks
involved not only in dynamic cellular processes, such as transcription and DNA repair, but …

Long noncoding RNAs (lncRNAs) are a relatively well‐characterized class of noncoding
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …

A wide spectrum of metabolites (mainly, the three major nutrients and their derivatives) can
be sensed by specific sensors, then trigger a series of signal transduction pathways and …

In mammalian cells, DNA methylation on the fifth position of cytosine (5mC) plays an
important role as an epigenetic mark. However, DNA methylation was considered to be …

Organisms require an appropriate balance of stability and reversibility in gene expression
programmes to maintain cell identity or to enable responses to stimuli; epigenetic regulation …

Epigenetics is the study of changes in gene activity that can be transmitted through cell
divisions but cannot be explained by changes in the DNA sequence. Epigenetic …

We report the identification of 67 previously undescribed histone modifications, increasing
the current number of known histone marks by about 70%. We further investigated one of the …

Several mechanisms have been proposed for histone marks to exert their functions,
including altering the physical properties of nucleosomes by neutralization of charge via …

This review describes new developments in the study of transgenerational epigenetic
inheritance, a component of epigenetics. We start by examining the basic concepts of the …