Development of a Single-Molecule Force Spectroscopy Technique for the Characterization of Protein-Carbohydrate Dissociation Forces
M Hackl - 2023 - search.proquest.com
Protein-carbohydrate interactions play a crucial role in all forms of life. Such interactions
regulate cellular processes, initiate viral infection of host cells, indicate cancer development …
regulate cellular processes, initiate viral infection of host cells, indicate cancer development …
Determining Genotypic and Phenotypic Factors Influencing Macrophage Tropism in the HIV-1 Envelope Protein
XA Bonner - 2024 - cdr.lib.unc.edu
Abstract The HIV-1 Envelope (Env) protein is organized as a heterotrimer composed of three
gp120 and three gp41 proteins on the surface of virus particles. Initially, when an individual …
gp120 and three gp41 proteins on the surface of virus particles. Initially, when an individual …
Mechanistic Insights into Coactivator Recruitment by Nuclear Receptors
ND Daffern - 2022 - search.proquest.com
Nuclear receptors (NRs) are an important family of transcription factors that often regulate
genes in response to ligands and by way of direct interactions with coactivator proteins …
genes in response to ligands and by way of direct interactions with coactivator proteins …
Caractérisation des mécanismes moléculaires impliqués dans la régulation des neutrophiles par le récepteur inhibiteur CLEC12A
J Vitry - 2022 - corpus.ulaval.ca
Résumé L'arthrite est une des principales causes d'invalidité et d'utilisation des soins de
santé au Canada. Environ 16% des Canadiens âgés de 15 ans et plus souffrent d'arthrite et …
santé au Canada. Environ 16% des Canadiens âgés de 15 ans et plus souffrent d'arthrite et …
Strength in Numbers: How Multivalent WW-PPXY Interactions Regulate Cell Signaling
AJ Vogel - 2022 - ir.library.oregonstate.edu
Cell signaling is often mediated by protein-protein interactions, which must be specific,
tunable, and transient to allow agile responsiveness to cellular messages. Due to their …
tunable, and transient to allow agile responsiveness to cellular messages. Due to their …
Atomistic Simulations and Deep Mutational Scanning of Protein Stability and Binding Interactions in the SARS-CoV-2 Spike Protein Complexes with Nanobodies …
GM Verkhivker, S Agajanian, DY Oztas, G Gupta - bioRxiv, 2021 - biorxiv.org
Structural and biochemical studies have recently revealed a range of rationally engineered
nanobodies with efficient neutralizing capacity against SARS-CoV-2 virus and resilience …
nanobodies with efficient neutralizing capacity against SARS-CoV-2 virus and resilience …
Design, synthesis and evaluation of tool compounds for studying endosulfatases
A Kennett - 2022 - ora.ox.ac.uk
The extracellular endo-6-O-sulfatases (Sulfs) catalyse the hydrolysis of the glucosamaine 6-
O-sulfate groups within heparan sulfate (HS). By controlling the sulfation status of HS, the …
O-sulfate groups within heparan sulfate (HS). By controlling the sulfation status of HS, the …
Dissecting Molecular Determinants of Mutational Escape Mechanisms in the SARS-CoV-2 Spike Protein Complexes with Nanobodies: Atomistic Simulations and …
G Verkhivker, S Agajanian, DY Oztas, G Gupta - 2021 - preprints.org
Structural and biochemical studies have recently revealed a range of rationally engineered
nanobodies with efficient neutralizing capacity against SARS-CoV-2 virus and resilience …
nanobodies with efficient neutralizing capacity against SARS-CoV-2 virus and resilience …
[图书][B] Avidity-based method for selective purification of monoubiquitinated recombinant proteins for biophysical analysis
SL Nelson - 2022 - search.proquest.com
Protein ubiquitination is a highly conserved posttranslational modification in which the
protein ubiquitin is covalently linked through an isopeptide bond to a lysine residue of the …
protein ubiquitin is covalently linked through an isopeptide bond to a lysine residue of the …