Network pharmacology: towards the artificial intelligence-based precision traditional Chinese medicine

P Zhang, D Zhang, W Zhou, L Wang… - Briefings in …, 2024 - academic.oup.com
Network pharmacology (NP) provides a new methodological perspective for understanding
traditional medicine from a holistic perspective, giving rise to frontiers such as traditional …

[HTML][HTML] Systems Theory-Driven Framework for AI Integration into the Holistic Material Basis Research of Traditional Chinese Medicine

J Zeng, X Jia - Engineering, 2024 - Elsevier
This research introduces a systems theory-driven framework to integration artificial
intelligence (AI) into traditional Chinese medicine (TCM) research, enhancing the …

Targeting ferroptosis unveils a new era for traditional Chinese medicine: a scientific metrology study

S Cao, Y Wei, Y Yue, Y Chen, S Liao, A Li… - Frontiers in …, 2024 - frontiersin.org
In the past 11 years, there has been a surge in studies exploring the regulatory effect of
Traditional Chinese Medicine (TCM) on ferroptosis. However, a significant gap persists in …

The pathological mechanisms and potential therapeutic drugs for myocardial ischemia reperfusion injury

S Zhang, F Yan, F Luan, Y Chai, N Li, YW Wang… - Phytomedicine, 2024 - Elsevier
Background Cardiovascular disease is the main cause of death and disability, with
myocardial ischemia being the predominant type that poses a significant threat to humans …

Community cohesion looseness in gene networks reveals individualized drug targets and resistance

S Wang, D Lee - Briefings in Bioinformatics, 2024 - academic.oup.com
Community cohesion plays a critical role in the determination of an individual's health in
social science. Intriguingly, a community structure of gene networks indicates that the …

[PDF][PDF] Uncovering the subtype-specific disease module and the development of drug response prediction models for glioma

S Munquad, AB Das - Heliyon, 2024 - cell.com
The poor prognosis of glioma patients brought attention to the need for effective therapeutic
approaches for precision therapy. Here, we deployed algorithms relying on network …

Multi-level advances in databases related to systems pharmacology in traditional Chinese medicine: a 60-year review

M Fan, C Jin, D Li, Y Deng, L Yao, Y Chen… - Frontiers in …, 2023 - frontiersin.org
The therapeutic effects of traditional Chinese medicine (TCM) involve intricate interactions
among multiple components and targets. Currently, computational approaches play a pivotal …

Endotype-driven Co-module mechanisms of danhong injection in the Co-treatment of cardiovascular and cerebrovascular diseases: A modular-based drug and …

S Zhang, Q Niu, W Zong, Q Song, S Tian… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Cardiovascular and cerebrovascular diseases are the
leading causes of death worldwide and interact closely with each other. Danhong Injection …

Potential ther apeutic effects of tr aditional Chinese medicine in acute mountain sickness: Pathogenesis, Mechanisms and futur e dir ections

Z Wu, Y Wang, R Gao, J Chen, Y Chen, M Li… - Frontiers in …, 2024 - frontiersin.org
Backgr ound and objectives: Acute mountain sickness (AMS) is a pathology with different
symptoms in which the organism is not adapted to the environment that occurs under the …

Hawthorn with “homology of medicine and food”: a review of anticancer effects and mechanisms

Z Zhou, Y Nan, X Li, P Ma, Y Du, G Chen… - Frontiers in …, 2024 - frontiersin.org
Over the past few years, there has been a gradual increase in the incidence of cancer,
affecting individuals at younger ages. With its refractory nature and substantial fatality rate …