Propofol: a review of its role in pediatric anesthesia and sedation

V Chidambaran, A Costandi, A D'Mello - CNS drugs, 2015 - Springer
Propofol is an intravenous agent used commonly for the induction and maintenance of
anesthesia, procedural, and critical care sedation in children. The mechanisms of action on …

Propofol vs. inhalational agents to maintain general anaesthesia in ambulatory and in-patient surgery: a systematic review and meta-analysis

S Schraag, L Pradelli, AJO Alsaleh, M Bellone… - BMC …, 2018 - Springer
Background It is unclear if anaesthesia maintenance with propofol is advantageous or
beneficial over inhalational agents. This study is intended to compare the effects of propofol …

Smoking and pain: pathophysiology and clinical implications

Y Shi, TN Weingarten, CB Mantilla… - The Journal of the …, 2010 - pubs.asahq.org
Cigarette smoke, which serves as a nicotine delivery vehicle in humans, produces profound
changes in physiology. Experimental studies suggest that nicotine has analgesic properties …

Influence of propofol‐based total intravenous anaesthesia on peri‐operative outcome measures: a narrative review

MG Irwin, CKE Chung, KY Ip, MD Wiles - Anaesthesia, 2020 - Wiley Online Library
Propofol‐based total intravenous anaesthesia is well known for its smooth, clear‐headed
recovery and anti‐emetic properties, but there are also many lesser known beneficial …

Prevention of chronic postoperative pain: cellular, molecular, and clinical insights for mechanism-based treatment approaches

R Deumens, A Steyaert, P Forget, M Schubert… - Progress in …, 2013 - Elsevier
Nearly every surgery can elicit a rather therapy-resistant chronic postoperative pain.
Preventive medicine is therefore anticipated with hopeful eyes, but requires a better …

Maintenance anaesthetics during remifentanil-based anaesthesia might affect postoperative pain control after breast cancer surgery

SW Shin, AR Cho, HJ Lee, HJ Kim… - British journal of …, 2010 - academic.oup.com
Background Although remifentanil provides profound analgesia during operation,
postoperative occurrence of hyperalgesia and tolerance after remifentanil administration …

Total intravenous anesthesia will supercede inhalational anesthesia in pediatric anesthetic practice

GR Lauder - Pediatric anesthesia, 2015 - Wiley Online Library
Inhalational anesthesia has dominated the practice of pediatric anesthesia. However, as the
introduction of agents such as propofol, short‐acting opioids, midazolam, and …

Does propofol anesthesia lead to less postoperative pain compared with inhalational anesthesia?: a systematic review and meta-analysis

K Peng, HY Liu, SR Wu, H Liu, ZC Zhang… - Anesthesia & …, 2016 - journals.lww.com
BACKGROUND: Many studies have compared propofol-based anesthesia with inhalational
anesthesia. Results from several studies have shown improved postoperative analgesia …

Effects of intra‐operative maintenance of general anaesthesia with propofol on postoperative pain outcomes–a systematic review and meta‐analysis

Q Qiu, SW Choi, SSC Wong, MG Irwin… - Anaesthesia, 2016 - Wiley Online Library
Propofol is used both for induction and maintenance of anaesthesia. Recent evidence
shows that propofol has analgesic properties. This meta‐analysis evaluated differences in …

Analgesic and sedative effects of intranasal dexmedetomidine in third molar surgery under local anaesthesia

CW Cheung, KFJ Ng, J Liu, MYV Yuen… - British journal of …, 2011 - academic.oup.com
Background Dexmedetomidine (DEX) is an alpha 2-adrenoreceptor agonist, which induces
sedation and analgesia. This study aimed to determine whether intranasal DEX offered …