Consensus on diagnosis and management of Cushing's disease: a guideline update

M Fleseriu, R Auchus, I Bancos… - The lancet Diabetes & …, 2021 - thelancet.com
Cushing's disease requires accurate diagnosis, careful treatment selection, and long-term
management to optimise patient outcomes. The Pituitary Society convened a consensus …

Causes, consequences, and treatment of metabolically unhealthy fat distribution

N Stefan - The lancet Diabetes & endocrinology, 2020 - thelancet.com
An increase in fat mass is considered to be an important risk factor for the worldwide
increase in type 2 diabetes and cardiovascular disease. However, for a given fat mass, there …

The multiple roles of life stress in metabolic disorders

M Kivimäki, A Bartolomucci, I Kawachi - Nature Reviews Endocrinology, 2023 - nature.com
The activation of stress-related neuroendocrine systems helps to maintain homeostasis, but
excessive stress can damage body functions. We review current evidence from basic …

Age-dependent and sex-dependent disparity in mortality in patients with adrenal incidentalomas and autonomous cortisol secretion: an international, retrospective …

T Deutschbein, G Reimondo, G Di Dalmazi… - The Lancet Diabetes & …, 2022 - thelancet.com
Background The association between cortisol secretion and mortality in patients with
adrenal incidentalomas is controversial. We aimed to assess all-cause mortality, prevalence …

Diagnosis and treatment of pituitary adenomas: a review

ME Molitch - Jama, 2017 - jamanetwork.com
Importance Pituitary adenomas may hypersecrete hormones or cause mass effects.
Therefore, early diagnosis and treatment are important. Observations Prevalence of pituitary …

Cortisol dysregulation: the bidirectional link between stress, depression, and type 2 diabetes mellitus

JJ Joseph, SH Golden - Annals of the New York Academy of …, 2017 - Wiley Online Library
Controversy exists over the role of stress and depression in the pathophysiology of type 2
diabetes mellitus. Depression has been shown to increase the risk for progressive insulin …

Efficacy and safety of osilodrostat in patients with Cushing's disease (LINC 3): a multicentre phase III study with a double-blind, randomised withdrawal phase

R Pivonello, M Fleseriu, J Newell-Price… - The Lancet Diabetes & …, 2020 - thelancet.com
Background Cushing's disease is a rare endocrine disorder characterised by cortisol
overproduction with severe complications. Therapies for cortisol reduction are often …

Sex disparities in COVID-19 severity and outcome: are men weaker or women stronger?

R Pivonello, RS Auriemma, C Pivonello, AM Isidori… - …, 2021 - karger.com
Abstract The coronavirus disease 2019 (COVID-19) outbreak, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global public health issue which has …

Understanding the relationships between physiological and psychosocial stress, cortisol and cognition

KA James, JI Stromin, N Steenkamp… - Frontiers in …, 2023 - frontiersin.org
Stress is viewed as a state of real or perceived threat to homeostasis, the management of
which involves the endocrine, nervous, and immune systems. These systems work …

COVID-19 and the endocrine system: a comprehensive review on the theme

G Lisco, A De Tullio, A Stragapede… - Journal of clinical …, 2021 - mdpi.com
Background and aim. The review aimed to summarize advances in the topic of endocrine
diseases and coronavirus disease 2019 (COVID-19). Methods. Scientific and institutional …