The persistence of HIV-1 latent reservoirs represents a major barrier to virus eradication in
infected patients under HAART since interruption of the treatment inevitably leads to a …

This review deals with clinical applications of compounds that inhibit the action of the
protease encoded within the genome of human immunodeficiency virus (HIV). The HIV …

Wound healing represents a well orchestrated reparative response that is induced by
injuries. Angiogenesis plays a central role in wound healing. In this work, we sought to …

Chronic wounds represent a major public health problem affecting 6.5 million people in the
United States. Ischemia, primarily caused by peripheral artery diseases, represents a major …

Abstract Background Unlike CD4+ T cells, HIV-1 infected macrophages exhibit extended life
span even upon stress, consistent with their in vivo role as long-lived HIV-1 reservoirs …

HIV infection is not curable with current antiretroviral therapy (ART) because a small fraction
of CD4+ T cells infected prior to ART initiation persists. Understanding the nature of this …

HIV-1 infection in memory CD4+ T cells forms a latent reservoir that is a barrier to cure.
Identification of immune biomarkers that correlate with HIV-1 reservoir size may aid with …

The major barrier to eradicating human immunodeficiency virus‐1 (HIV) infection is the
generation and extended survival of HIV reservoirs. In order to eradicate HIV infection, it is …

Serially-sampled nucleotide sequences can be used to infer demographic history of
evolving viral populations. The shape of a phylogenetic tree often reflects the interplay …

Purpose. This study is dedicated to the permeation of various amino acid-, D-glucose-, and
PEG-conjugates of indinavir, saquinavir, and nelfinavir across monolayers of Caco-2 cells …