Spermatogonial stem cells (SSCs) are crucial for maintaining spermatogenesis throughout
life, and understanding how these cells function has important implications for …

It has been one and a half centuries since Enrico Sertoli published the seminal discovery of
the testicular 'nurse cell', not only a key cell in the testis, but indeed one of the most amazing …

BACKGROUND Infertility is an important side effect of treatments used for cancer and other
non-malignant conditions in males. This may be due to the loss of spermatogonial stem cells …

STUDY QUESTION What clinical practices, patient management strategies and
experimental methods are currently being used to preserve and restore the fertility of …

Spermatogenesis originates from spermatogonial stem cells (SSCs). Development of the
spermatogonial transplantation technique in 1994 provided the first functional assay to …

Context Young boys treated with high-dose chemotherapy are often confronted with infertility
once they reach adulthood. Cryopreserving testicular tissue before chemotherapy and …

A decade ago, we first reported that endometrial biopsy significantly improves the success of
pregnancy in IVF patients with recurrent implantation failure, an observation that was later …

Spermatogenesis, an elaborate and male-specific process in adult testes by which a number
of spermatozoa are produced constantly for male fertility, relies on spermatogonial stem …

Spermatogonial stem cells (SSCs) undergo self-renewal divisions to support
spermatogenesis. Although several in vitro SSC culture systems have been developed …

Spermatogenesis, an elaborate and male-specific process in adult testes by which a number
of spermatozoa are produced constantly for male fertility, relies on spermatogonial stem …